Evidence map›Paper›PMID 33287236›Full record

ReviewPolymers2020

Topographical and Biomechanical Guidance of Electrospun Fibers for Biomedical Applications.

Sara Ferraris, Silvia Spriano, Alessandro Calogero Scalia, Andrea Cochis, Lia Rimondini, Iriczalli Cruz-Maya, Vincenzo Guarino, Alessio Varesano, Claudia Vineis

Abstract readReview
In one paragraph

Review in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sara FerrarisDepartment of Applied Science and Technology, Politecnico di Torino, 10129 Torino, Italy.ORCID 0000-0001-8316-5406
Silvia SprianoDepartment of Applied Science and Technology, Politecnico di Torino, 10129 Torino, Italy.ORCID 0000-0002-7367-9777
Alessandro Calogero ScaliaDepartment of Health Sciences, Center for Translational Research on Autoimmune and Allergic Diseases-CAAD, Università del Piemonte Orientale UPO, 28100 Novara, Italy.
Andrea CochisDepartment of Health Sciences, Center for Translational Research on Autoimmune and Allergic Diseases-CAAD, Università del Piemonte Orientale UPO, 28100 Novara, Italy.ORCID 0000-0003-2455-8239
Lia RimondiniDepartment of Health Sciences, Center for Translational Research on Autoimmune and Allergic Diseases-CAAD, Università del Piemonte Orientale UPO, 28100 Novara, Italy.ORCID 0000-0002-7785-2282
Iriczalli Cruz-MayaInstitute for Polymers, Composites and Biomaterials (IPCB), National Research Council of Italy, Mostra d'Oltremare, Pad. 20, V. le J.F. Kennedy 54, 80125 Napoli, Italy.ORCID 0000-0001-6366-3002
Vincenzo GuarinoInstitute for Polymers, Composites and Biomaterials (IPCB), National Research Council of Italy, Mostra d'Oltremare, Pad. 20, V. le J.F. Kennedy 54, 80125 Napoli, Italy.ORCID 0000-0003-1546-3721
Alessio VaresanoInstitute of Intelligent Industrial Technologies and Systems for Advanced Manufacturing (STIIMA), National Research Council of Italy (CNR), Corso Giuseppe Pella 16, 13900 Biella, Italy.ORCID 0000-0002-5497-4842
Claudia VineisInstitute of Intelligent Industrial Technologies and Systems for Advanced Manufacturing (STIIMA), National Research Council of Italy (CNR), Corso Giuseppe Pella 16, 13900 Biella, Italy.ORCID 0000-0003-4670-5586

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electrospinning is gaining increasing interest in the biomedical field as an eco-friendly and economic technique for production of random and oriented polymeric fibers. The aim of this review was to give an overview of electrospinning potentialities in the production of fibers for biomedical applications with a focus on the possibility to combine biomechanical and topographical stimuli. In fact, selection of the polymer and the eventual surface modification of the fibers allow selection of the proper chemical/biological signal to be administered to the cells. Moreover, a proper design of fiber orientation, dimension, and topography can give the opportunity to drive cell growth also from a spatial standpoint. At this purpose, the review contains a first introduction on potentialities of electrospinning for the obtainment of random and oriented fibers both with synthetic and natural polymers. The biological phenomena which can be guided and promoted by fibers composition and topography are in depth investigated and discussed in the second section of the paper. Finally, the recent strategies developed in the scientific community for the realization of electrospun fibers and for their surface modification for biomedical application are presented and discussed in the last section.

Indexed as

biochemical guidancecontact guidanceelectrospinningfunctionalizationimplantable devicesoriented fibersrandom fiberstopographical guidance

Identifiers

PMID33287236
PMCPMC7761715

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.