Evidence map›Paper›PMID 33287173›Full record

ArticleInternational journal of molecular sciences2020

Deficit in Adipose Differentiation in Mesenchymal Stem Cells Derived from Chronic Rhinosinusitis Nasal Polyps Compared to Nasal Mucosal Tissue.

Emanuela Chiarella, Nicola Lombardo, Nadia Lobello, Giovanna Lucia Piazzetta, Helen Linda Morrone, Maria Mesuraca, Heather Mandy Bond

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Immunological Aspects of Chronic Rhinosinusitis.Diagnostics (Basel, Switzerland) · 2022
    Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Emanuela ChiarellaLaboratory of Molecular Haematopoiesis and Stem Cell Biology, Department of Experimental and Clinical Medicine, University "Magna Græcia", 88100 Catanzaro, Italy.ORCID 0000-0002-8314-715X
Nicola LombardoOtolaryngology Head and Neck Surgery, Department Medical and Surgical Sciences, University "Magna Græcia", 88100 Catanzaro, Italy.ORCID 0000-0003-4479-399X
Nadia LobelloOtolaryngology Head and Neck Surgery, Department Medical and Surgical Sciences, University "Magna Græcia", 88100 Catanzaro, Italy.
Giovanna Lucia PiazzettaOtolaryngology Head and Neck Surgery, Department Medical and Surgical Sciences, University "Magna Græcia", 88100 Catanzaro, Italy.
Helen Linda MorroneLaboratory of Molecular Haematopoiesis and Stem Cell Biology, Department of Experimental and Clinical Medicine, University "Magna Græcia", 88100 Catanzaro, Italy.
Maria MesuracaLaboratory of Molecular Haematopoiesis and Stem Cell Biology, Department of Experimental and Clinical Medicine, University "Magna Græcia", 88100 Catanzaro, Italy.ORCID 0000-0002-5455-168X
Heather Mandy BondLaboratory of Molecular Haematopoiesis and Stem Cell Biology, Department of Experimental and Clinical Medicine, University "Magna Græcia", 88100 Catanzaro, Italy.ORCID 0000-0003-4033-2985
Magna Graecia University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic rhinosinusitis of the nasal mucosa is an inflammatory disease of paranasal sinuses, which causes rhinorrhea, nasal congestion, and hyposmia, and in some cases, it can result in the development of nasal polyposis. Nasal polyps are benign lobular-shaped growths that project in the nasal cavities; they originate from inflammation in the paranasal mucous membrane and are associated with a high expression of interleukins (IL)-4, IL-5, IL-13, and IgE. Polyps derive from the epithelial-mesenchymal transition of the nasal epithelium resulting in a nasal tissue remodeling. Nasal polyps from three patients with chronic rhinosinusitis as well as control non-polyp nasal mucosa were used to isolate and cultivate mesenchymal stem cells characterized as CD73

Indexed as

AdipogenesisCell DifferentiationAdipocytesApoptosisBiomarkersBiopsyCell ProliferationChronic DiseaseDisease SusceptibilityHumansImmunophenotypingMesenchymal Stem CellsNasal MucosaNasal PolypsRhinitisSinusitisBiomarkersadipocyte differentiationapoptosismesenchymal cellsnasal polyps

Identifiers

PMID33287173
PMCPMC7730671
OpenAlexW3107659516

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.