Evidence map›Paper›PMID 33287166›Full record

ArticleInternational journal of molecular sciences2020

On the Single-Crystal Structure of Tenofovir Alafenamide Mono-Fumarate: A Metastable Phase Featuring a Mixture of Co-Crystal and Salt.

Jian-Wei Wang, Lu Liu, Ka-Xi Yu, Hong-Zhen Bai, Jun Zhou, Wen-Hua Zhang, Xiurong Hu, Guping Tang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jian-Wei WangDepartment of Chemistry, Zhejiang University, Hangzhou 310028, China.
Lu LiuDepartment of Chemistry, Zhejiang University, Hangzhou 310028, China.
Ka-Xi YuDepartment of Chemistry, Zhejiang University, Hangzhou 310028, China.
Hong-Zhen BaiDepartment of Chemistry, Zhejiang University, Hangzhou 310028, China.
Jun ZhouDepartment of Chemistry, Zhejiang University, Hangzhou 310028, China.
Wen-Hua ZhangCollege of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China.ORCID 0000-0001-9047-8881
Xiurong HuDepartment of Chemistry, Zhejiang University, Hangzhou 310028, China.
Guping TangDepartment of Chemistry, Zhejiang University, Hangzhou 310028, China.
Zhejiang University · CNSoochow University · CN

Funding

National Natural Science Foundation of China 51873185
6 · The paper itself

Abstract

Tenofovir alafenamide (TAF) is a prodrug of tenofovir as a potent nucleotide reverse transcriptase inhibitor. It serves as the key component of Genvoya

Indexed as

Models, MolecularAnti-HIV AgentsChemistry Techniques, SyntheticCrystallography, X-RayFumaratesMolecular ConformationMolecular StructureSaltsSpectrum AnalysisTenofovirAnti-HIV AgentsFumaratesSaltsTenofoviranti-HIV drugchronic hepatitis Bfumaric acidHirshfeld analysishydrogen-bondingnucleotide reverse transcriptase inhibitorpharmaceutical co-crystaltenofovir alafenamide

Identifiers

PMID33287166
PMCPMC7730268
OpenAlexW3106847676

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.