Evidence map›Paper›PMID 33287133›Full record

ReviewSensors (Basel, Switzerland)2020

DNA Origami-Enabled Biosensors.

Shuang Wang, Zhaoyu Zhou, Ningning Ma, Sichang Yang, Kai Li, Chao Teng, Yonggang Ke, Ye Tian

Abstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Dynamic Control of DNA Origami Self-Assembly by Transcriptional Modules.Journal of the American Chemical Society · 2026
    Article
  6. The effect of long-term ambient storage on the morphology of adhered DNA origami.Computational and structural biotechnology journal · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Modular DNA origami-based electrochemical detection of DNA and proteins.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  13. DNA Origami Vesicle Sensors with Triggered Single-Molecule Cargo Transfer.Angewandte Chemie (International ed. in English) · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shuang WangInstitute of Marine Biomedicine, Shenzhen Polytechnic, Shenzhen 518055, China.
Zhaoyu ZhouState Key Laboratory of Analytical Chemistry for Life Science, College of Engineering and Applied Sciences, Nanjing University, Nanjing 210023, China.
Ningning MaState Key Laboratory of Analytical Chemistry for Life Science, College of Engineering and Applied Sciences, Nanjing University, Nanjing 210023, China.
Sichang YangState Key Laboratory of Analytical Chemistry for Life Science, College of Engineering and Applied Sciences, Nanjing University, Nanjing 210023, China.
Kai LiInstitute of Marine Biomedicine, Shenzhen Polytechnic, Shenzhen 518055, China.
Chao TengInstitute of Marine Biomedicine, Shenzhen Polytechnic, Shenzhen 518055, China.
Yonggang KeWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30322, USA.
Ye TianState Key Laboratory of Analytical Chemistry for Life Science, College of Engineering and Applied Sciences, Nanjing University, Nanjing 210023, China.

Funding

Shenzhen International Cooperation Research Project (No. GJHZ20180930090602235, GJHZ20190819151807167).
6 · The paper itself

Abstract

Biosensors are small but smart devices responding to the external stimulus, widely used in many fields including clinical diagnosis, healthcare and environment monitoring, etc. Moreover, there is still a pressing need to fabricate sensitive, stable, reliable sensors at present. DNA origami technology is able to not only construct arbitrary shapes in two/three dimension but also control the arrangement of molecules with different functionalities precisely. The functionalization of DNA origami nanostructure endows the sensing system potential of filling in weak spots in traditional DNA-based biosensor. Herein, we mainly review the construction and sensing mechanisms of sensing platforms based on DNA origami nanostructure according to different signal output strategies. It will offer guidance for the application of DNA origami structures functionalized by other materials. We also point out some promising directions for improving performance of biosensors.

Indexed as

Biosensing TechniquesDNANanostructuresNanotechnologyNucleic Acid ConformationDNAchiralityDNA nanotechnologyDNA origamiFRETnanoporesensorSERS

Identifiers

PMID33287133
PMCPMC7731452

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.