Evidence map›Paper›PMID 33287124›Full record

ArticleDiagnostics (Basel, Switzerland)2020

Differential Diagnosis of Preeclampsia Based on Urine Peptidome Features Revealed by High Resolution Mass Spectrometry.

Alexey S Kononikhin, Natalia V Zakharova, Viktoria A Sergeeva, Maria I Indeykina, Natalia L Starodubtseva, Anna E Bugrova, Kamila T Muminova, Zulfia S Khodzhaeva, Igor A Popov, Wenguang Shao and 5 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Current Challenges and Future Directions in Peptidomics.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Urinary Protein and Peptide Markers in Chronic Kidney Disease.International journal of molecular sciences · 2021
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Alexey S KononikhinSkolkovo Institute of Science and Technology, 143026 Moscow, Russia.
Natalia V ZakharovaEmanuel Institute for Biochemical Physics, Russian Academy of Sciences, 119334 Moscow, Russia.
Viktoria A SergeevaEmanuel Institute for Biochemical Physics, Russian Academy of Sciences, 119334 Moscow, Russia.
Maria I IndeykinaEmanuel Institute for Biochemical Physics, Russian Academy of Sciences, 119334 Moscow, Russia.
Natalia L StarodubtsevaV.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Healthcare of the Russian Federation, 117198 Moscow, Russia.
Anna E BugrovaV.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Healthcare of the Russian Federation, 117198 Moscow, Russia.
Kamila T MuminovaV.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Healthcare of the Russian Federation, 117198 Moscow, Russia.
Zulfia S KhodzhaevaV.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Healthcare of the Russian Federation, 117198 Moscow, Russia.
Igor A PopovV.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Healthcare of the Russian Federation, 117198 Moscow, Russia.
Wenguang ShaoInstitute of Molecular Systems Biology, ETH Zurich, 8092 Zurich, Switzerland.
Patrik PedrioliInstitute of Molecular Systems Biology, ETH Zurich, 8092 Zurich, Switzerland.
Roman G ShmakovV.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Healthcare of the Russian Federation, 117198 Moscow, Russia.
Vladimir E FrankevichV.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Healthcare of the Russian Federation, 117198 Moscow, Russia.
Gennady T SukhikhV.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Healthcare of the Russian Federation, 117198 Moscow, Russia.
Evgeny N NikolaevSkolkovo Institute of Science and Technology, 143026 Moscow, Russia.
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I.Kulakov of the Ministry of Healthcare of the Russian Federation · RUInstitute of Biochemical Physics NM Emanuel · RUETH Zurich · CHMoscow Institute of Physics and Technology · RUSemenov Institute of Chemical Physics · RUSkolkovo Institute of Science and Technology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preeclampsia (PE) is a severe pregnancy complication, which may be considered as a systemic response in the second half of pregnancy to physiological failures in the first trimester, and can lead to very serious consequences for the health of the mother and fetus. Since PE is often associated with proteinuria, urine proteomic assays may represent a powerful tool for timely diagnostics and appropriate management. High resolution mass spectrometry was applied for peptidome analysis of 127 urine samples of pregnant women with various hypertensive complications: normotensive controls (

Indexed as

hypertensionmass-spectrometrypreeclampsiaproteomicsurine peptidomics

Identifiers

PMID33287124
PMCPMC7761751
OpenAlexW3107937417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.