Evidence map›Paper›PMID 33286803›Full record

ArticleEntropy (Basel, Switzerland)2020

Fever Time Series Analysis Using Slope Entropy. Application to Early Unobtrusive Differential Diagnosis.

David Cuesta-Frau, Pradeepa H Dakappa, Chakrapani Mahabala, Arjun R Gupta

Abstract read
In one paragraph

Article in Entropy (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Slope Entropy Characterisation: The Role of theEntropy (Basel, Switzerland) · 2022
    Article
  8. Article
  9. Article
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  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

David Cuesta-FrauTechnological Institute of Informatics, Universitat Politècnica de València, Alcoi Campus, 03801 Alcoi, Spain.ORCID 0000-0002-0076-0515
Pradeepa H DakappaClinical Pharmacology, Nanjappa Hospitals, Shimoga 91903, India.ORCID 0000-0002-5741-1885
Chakrapani MahabalaDepartment of Medicine, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal 575001, India.ORCID 0000-0002-0460-7913
Arjun R GuptaDepartment of Medicine, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal 575001, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fever is a readily measurable physiological response that has been used in medicine for centuries. However, the information provided has been greatly limited by a plain thresholding approach, overlooking the additional information provided by temporal variations and temperature values below such threshold that are also representative of the subject status. In this paper, we propose to utilize continuous body temperature time series of patients that developed a fever, in order to apply a method capable of diagnosing the specific underlying fever cause only by means of a pattern relative frequency analysis. This analysis was based on a recently proposed measure, Slope Entropy, applied to a variety of records coming from dengue and malaria patients, among other fever diseases. After an input parameter customization, a classification analysis of malaria and dengue records took place, quantified by the Matthews Correlation Coefficient. This classification yielded a high accuracy, with more than 90% of the records correctly labelled in some cases, demonstrating the feasibility of the approach proposed. This approach, after further studies, or combined with more measures such as Sample Entropy, is certainly very promising in becoming an early diagnosis tool based solely on body temperature temporal patterns, which is of great interest in the current Covid-19 pandemic scenario.

Indexed as

body temperaturedenguedifferential diagnosisfevermalariaMatthews Correlation CoefficientSlope Entropytime series classification

Identifiers

PMID33286803
PMCPMC7597093

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.