Evidence map›Paper›PMID 33286163›Full record

ArticleEntropy (Basel, Switzerland)2020

Information Bottleneck for Estimating Treatment Effects with Systematically Missing Covariates.

Sonali Parbhoo, Mario Wieser, Aleksander Wieczorek, Volker Roth

Abstract read
In one paragraph

Article in Entropy (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Learning Extremal Representations with Deep Archetypal Analysis.International journal of computer vision · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sonali ParbhooDepartment of Mathematics and Computer Science, University of Basel, Basel CH 4051, Switzerland.ORCID 0000-0001-8400-3732
Mario WieserDepartment of Mathematics and Computer Science, University of Basel, Basel CH 4051, Switzerland.ORCID 0000-0002-8737-3605
Aleksander WieczorekDepartment of Mathematics and Computer Science, University of Basel, Basel CH 4051, Switzerland.ORCID 0000-0003-1565-1781
Volker RothDepartment of Mathematics and Computer Science, University of Basel, Basel CH 4051, Switzerland.

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung P2BSP2_184359SystemsX.ch 51MRP0158328
6 · The paper itself

Abstract

Estimating the effects of an intervention from high-dimensional observational data is a challenging problem due to the existence of confounding. The task is often further complicated in healthcare applications where a set of observations may be entirely missing for certain patients at test time, thereby prohibiting accurate inference. In this paper, we address this issue using an approach based on the information bottleneck to reason about the effects of interventions. To this end, we first train an information bottleneck to perform a low-dimensional compression of covariates by explicitly considering the relevance of information for treatment effects. As a second step, we subsequently use the compressed covariates to perform a transfer of relevant information to cases where data are missing during testing. In doing so, we can reliably and accurately estimate treatment effects even in the absence of a full set of covariate information at test time. Our results on two causal inference benchmarks and a real application for treating sepsis show that our method achieves state-of-the-art performance, without compromising interpretability.

Indexed as

average treatment effectcausal effectconfoundinghealthcareinformation bottleneckmutual informationsufficient covariatesystematically missing

Identifiers

PMID33286163
PMCPMC7516862

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.