Evidence map›Paper›PMID 33285872›Full record

ReviewEntropy (Basel, Switzerland)2020

A Review of the Application of Information Theory to Clinical Diagnostic Testing.

William A Benish

Abstract readReview
In one paragraph

Review in Entropy (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Association of HbADiabetologia · 2026
    Article
  3. Article
  4. Information Theory-Guided Detection of Biomarkers Using Programmable Aptamer Arrays.medRxiv : the preprint server for health sciences · 2025
    Article
  5. Article
  6. Review
  7. The injury severity score: an operations perspective.BMC medical research methodology · 2022
    Article
  8. Article
  9. Article
  10. Applications of Information Theory to Epidemiology.Entropy (Basel, Switzerland) · 2020
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

William A BenishDepartment of Internal Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.ORCID 0000-0003-2049-5437

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The fundamental information theory functions of entropy, relative entropy, and mutual information are directly applicable to clinical diagnostic testing. This is a consequence of the fact that an individual's disease state and diagnostic test result are random variables. In this paper, we review the application of information theory to the quantification of diagnostic uncertainty, diagnostic information, and diagnostic test performance. An advantage of information theory functions over more established test performance measures is that they can be used when multiple disease states are under consideration as well as when the diagnostic test can yield multiple or continuous results. Since more than one diagnostic test is often required to help determine a patient's disease state, we also discuss the application of the theory to situations in which more than one diagnostic test is used. The total diagnostic information provided by two or more tests can be partitioned into meaningful components.

Indexed as

entropyinformation theorymultiple diagnostic testsmutual informationrelative entropy

Identifiers

PMID33285872
PMCPMC7516534

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.