ArticlePLoS biology2020
Prior expectations evoke stimulus-specific activity in the deep layers of the primary visual cortex.
Article in PLoS biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed, 144 citations in OpenAlex.
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- Expectation Exerts Flexible and Context-dependent Influence on Conscious Object Recognition.Journal of cognitive neuroscience · 2026Article
- The primate claustrum as a hub for precision weighting of prediction errors across the cortical hierarchy.PLoS biology · 2026Article
- Predictive acoustical processing in human cortical layers.Nature communications · 2026Article
- UltraFast Layer-Resolved Encoding (uFLARE) functional MRI deciphers bidirectional signaling from spontaneous activity.Nature communications · 2026Article
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- The potential of laminar functional MRI in refining the understanding of epilepsy in humans.Brain : a journal of neurology · 2025Review
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- Cortical-layer EEG-fMRI at 7T: experimental setup and analysis pipeline to elucidate generating mechanisms of alpha oscillations.bioRxiv : the preprint server for biology · 2025Article
- Experienced meditators show greater forward traveling cortical alpha wave strengths.Annals of the New York Academy of Sciences · 2025Article
- Neural evidence that humans reuse strategies to solve new tasks.PLoS biology · 2025Article
- Communication of perceptual predictions from the hippocampus to the deep layers of the parahippocampal cortex.Science advances · 2025Article
- In the brain of the beholder: bi-stable motion reveals mesoscopic-scale feedback modulation in V1.Brain structure & function · 2025Article
- How Layer-Specific fMRI Can Contribute to Understanding Perceptual Disturbances Across Psychiatric Disorders.Current topics in behavioral neurosciences · 2025Review
- Cortical travelling waves relate to variation in personality traits.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Hierarchical surprise signals in naturalistic violation of expectations.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Viewed touch influences tactile detection by altering decision criterion.Attention, perception & psychophysics · 2024Article
- Dynamic layer-specific processing in the prefrontal cortex during working memory.Communications biology · 2024Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
The way we perceive the world is strongly influenced by our expectations. In line with this, much recent research has revealed that prior expectations strongly modulate sensory processing. However, the neural circuitry through which the brain integrates external sensory inputs with internal expectation signals remains unknown. In order to understand the computational architecture of the cortex, we need to investigate the way these signals flow through the cortical layers. This is crucial because the different cortical layers have distinct intra- and interregional connectivity patterns, and therefore determining which layers are involved in a cortical computation can inform us on the sources and targets of these signals. Here, we used ultra-high field (7T) functional magnetic resonance imaging (fMRI) to reveal that prior expectations evoke stimulus-specific activity selectively in the deep layers of the primary visual cortex (V1). These findings are in line with predictive processing theories proposing that neurons in the deep cortical layers represent perceptual hypotheses and thereby shed light on the computational architecture of cortex.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.