Evidence map›Paper›PMID 33284732›Full record

ArticleJCO oncology practice2021

Out-of-Pocket Costs for Tyrosine Kinase Inhibitors and Patient Outcomes in

Bernardo H L Goulart, Joseph M Unger, Shasank Chennupati, Catherine R Fedorenko, Scott D Ramsey

Abstract read
In one paragraph

Article in JCO oncology practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bernardo H L GoulartHutchinson Institute for Cancer Outcomes Research (HICOR), Seattle, WA.
Joseph M UngerFred Hutchinson Cancer Research Center, Seattle, WA.
Shasank ChennupatiHutchinson Institute for Cancer Outcomes Research (HICOR), Seattle, WA.
Catherine R FedorenkoHutchinson Institute for Cancer Outcomes Research (HICOR), Seattle, WA.
Scott D RamseyHutchinson Institute for Cancer Outcomes Research (HICOR), Seattle, WA.

Funding

Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Marian Esvelt · 1985 to 2026
$296.4M
SWOG NCORP Research BaseUG1CA189974 · NCI · THE HOPE FOUNDATION · PI CHARLES D. BLANKE, DAWN HERSHMAN · 2014 to 2026
$80.6M
NCI NIH HHS P30 CA015704NCI NIH HHS UG1 CA189974
6 · The paper itself

Abstract

purposeWe investigated the association of out-of-pocket (OOP) costs for tyrosine kinase inhibitors (TKIs) with overall survival (OS) in epidermal growth factor receptor (

methodsWe used the Hutchinson Institute for Cancer Outcomes Research registry-claims database to identify patients with stage IV

resultsSeventy-eight and twenty-seven patients comprised the Q1-3 and Q4 groups, respectively. Median monthly TKI OOP costs were $1,431 (Q1-3)

conclusionAmong patients with advanced

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsAnaplastic Lymphoma KinaseErbB ReceptorsHealth ExpendituresHumansMutationProtein Kinase InhibitorsAnaplastic Lymphoma KinaseEGFR protein, humanErbB ReceptorsProtein Kinase Inhibitors

Identifiers

PMID33284732
PMCPMC8257903

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.