Evidence map›Paper›PMID 33284418›Full record

ArticleEuropean journal of pediatrics2021

Umbilical cord medication in healthy full-term newborns: a before-after uncontrolled quality improvement study.

Alessandra Coscia, Giovanni Boscarino, Maria Di Chiara, Francesca Faccioli, Roberto Pedicino, Elisa Onestà, Antonella Giancotti, Violante Di Donato, Benedetta Ronchi, Francesca Zantonelli and 3 more

Open access · hybridAbstract read
In one paragraph

Article in European journal of pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Alessandra CosciaNeonatology Unit, Department of Public Health and Pediatrics, University of Turin, Turin, Italy.
Giovanni BoscarinoDepartment of Maternal and Child Health Policlinico Umberto I, University La Sapienza, Rome, Italy. giovanni.boscarino@yahoo.com.ORCID http://orcid.org/0000-0003-2481-0692
Maria Di ChiaraDepartment of Maternal and Child Health Policlinico Umberto I, University La Sapienza, Rome, Italy.
Francesca FaccioliDepartment of Maternal and Child Health Policlinico Umberto I, University La Sapienza, Rome, Italy.
Roberto PedicinoDepartment of Maternal and Child Health Policlinico Umberto I, University La Sapienza, Rome, Italy.
Elisa OnestàDepartment of Maternal and Child Health Policlinico Umberto I, University La Sapienza, Rome, Italy.
Antonella GiancottiDepartment of Maternal and Child Health Policlinico Umberto I, University La Sapienza, Rome, Italy.
Violante Di DonatoDepartment of Maternal and Child Health Policlinico Umberto I, University La Sapienza, Rome, Italy.
Benedetta RonchiDepartment of Maternal and Child Health Policlinico Umberto I, University La Sapienza, Rome, Italy.
Francesca ZantonelliDepartment of Maternal and Child Health Policlinico Umberto I, University La Sapienza, Rome, Italy.
Alessia RussoDepartment of Maternal and Child Health Policlinico Umberto I, University La Sapienza, Rome, Italy.
Chiara MezzapiastraDepartment of Maternal and Child Health Policlinico Umberto I, University La Sapienza, Rome, Italy.
Gianluca TerrinDepartment of Maternal and Child Health Policlinico Umberto I, University La Sapienza, Rome, Italy.
Policlinico Umberto I · ITUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Umbilical cord care can be a stressful practice for parents. Complications of cord care can increase neonatal morbidity and mortality. The extracts of Arnica montana (AM) have been reported to possess antibacterial, anti-inflammatory, antifungal, and immunomodulatory activities. We aim to demonstrate the efficacy of AM on cord detachment and parents' stress level induced by cord medication in healthy full-term newborns. We enrolled full-term infants with a birth weight ≥ 2500 g in healthy conditions. Cord stumps of infants in the PRE-group were cleaned and dried, while cord stumps of infants in the POST-group were cleaned, dried, and medicated with a natural topic dermo-protective powder containing AM. After discharge, we interviewed parents on the stump status during follow-up visits in a pediatric office at 7 and 14 days of life, or by phone calls after follow-up visits. Long-rank test showed that time of cord separation of newborns in the PRE-group was significantly higher compared to that in the POST-group (p < 0.001). Parents of newborns in the PRE-group were significantly more stressed during cord medication compared to parents in the POST-group (2.0 (1.2 to 2.1) vs 1.0 (0.8 to 1.3), p = 0.011). Multivariate analysis showed a significantly linear relation with group assignment for cord separation (p < 0.001) and parents' stress during the medication (p = 0.033).Conclusion: The use of a natural topic dermo-protective powder containing AM reduces the time of cord separation, improves parents' stress level, and reduces the risk of complications. What is Known: • Cord stump care can be a stressful practice for parents. • Antiseptic treatment recommended for cord care could be associated with side effects such as burning and sensitization. What is New: • The medication of cord stump with a natural topic dermo-protective powder containing Arnica montana reduces time of cord detachment and of complication such as redness', bleeding, or secretions. • The use of Arnica montana for cord medication may have a positive impact on the family, reducing parents' stress, and the use of other medications.

Indexed as

Anti-Infective Agents, LocalQuality ImprovementAdministration, TopicalChildHumansInfantInfant, NewbornUmbilical CordAnti-Infective Agents, LocalArnica montanaComplicationsCord detachmentCord stumpNewbornsOmphalitisParents’ stress

Identifiers

PMID33284418
PMCPMC7813727
OpenAlexW3111635240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.