Evidence map›Paper›PMID 33284392›Full record

ArticleAnnals of intensive care2020

Are single-lumen 5Fr and triple-lumen 6Fr PICCs suitable for hemodynamic assessment by trans-pulmonary thermodilution? A pilot study.

Sonia D'Arrigo, Claudio Sandroni, Sofia Cacciola, Antonio Maria Dell'Anna, Mauro Pittiruti, Maria Giuseppina Annetta, Cesare Colosimo, Massimo Antonelli

Registry-linked trialAbstract read
In one paragraph

Article in Annals of intensive care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04241926 (Single-lumen 5Fr and Triple-lumen 6Fr PICCs Are Accurate for Hemodynamic), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04241926 nacompletednot on this map

Single-lumen 5Fr and Triple-lumen 6Fr PICCs Are Accurate for Hemodynamic

TypeinterventionalSponsorFondazione Policlinico Universitario Agostino Gemelli IRCCSRan2019 to 2020Enrolled15ConditionsPeripherally Inserted Central Catheters, Centrally Inserted Central Catheter, Transpulmonary Thermodilution, Hemodynamic MonitoringArmstranspolmonary thermodilution
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sonia D'ArrigoDepartment of Intensive Care, Emergency Medicine and Anesthesiology, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Largo Agostino Gemelli, 8, 00168, Rome, Italy. sonia.darrigo@policlinicogemelli.it.ORCID 0000-0001-6740-3195
Claudio SandroniDepartment of Intensive Care, Emergency Medicine and Anesthesiology, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Largo Agostino Gemelli, 8, 00168, Rome, Italy.
Sofia CacciolaDepartment of Intensive Care, Emergency Medicine and Anesthesiology, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Largo Agostino Gemelli, 8, 00168, Rome, Italy.
Antonio Maria Dell'AnnaDepartment of Intensive Care, Emergency Medicine and Anesthesiology, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Largo Agostino Gemelli, 8, 00168, Rome, Italy.
Mauro PittirutiDepartment of Surgery, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
Maria Giuseppina AnnettaDepartment of Intensive Care, Emergency Medicine and Anesthesiology, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Largo Agostino Gemelli, 8, 00168, Rome, Italy.
Cesare ColosimoDepartment of Radiology, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
Massimo AntonelliDepartment of Intensive Care, Emergency Medicine and Anesthesiology, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Largo Agostino Gemelli, 8, 00168, Rome, Italy.

Funding

Università Cattolica del Sacro Cuore D.1-2017
6 · The paper itself

Abstract

backgroundSingle-lumen 4Fr or double-lumen 5Fr power injectable peripherally inserted central catheters (PICCs) are not accurate for trans-pulmonary thermodilution (TPTD), since they overestimate cardiac index and other TPTD-derived parameters when compared with centrally inserted central catheters (CICCs) because of the smaller size of their lumen. We hypothesize that PICCs with larger lumen size may be reliable for the cardiac index assessment using the TPTD.

methodsThis is a single-centre, prospective method-comparison study that included adult patients admitted in ICU who required a calibrated Pulse Contour hemodynamic monitoring system (VolumeView/EV1000™) for circulatory shock and had both PICC and CICC in place. We compared TPTD measurements via single-lumen 5Fr or triple-lumen 6Fr polyurethane power injectable PICCs with triple-lumen 7Fr CICC (reference standard). To rule out biases related to manual injection, measurements were repeated using an automated rapid injection system. We performed Bland-Altman analysis accounting for multiple observations per patient.

resultsA total of 320 measurements were performed in 15 patients. During the manual phase, the cardiac index measured with either single-lumen 5Fr or triple-lumen 6Fr PICCs were comparable with cardiac index measured with triple-lumen 7Fr CICC (3.2 ± 1.04 vs. 3.2 ± 1.06 L/min/m

conclusionsDuring hemodynamic monitoring with TPTD, both single-lumen 5Fr PICCs and triple-lumen 6Fr PICCs can be used for cold fluid bolus injection as an alternative to CICC (ClinicalTrials.gov NCT04241926).

Indexed as

Cardiac outputCentrally inserted central catheterHemodynamic monitoringIntensive care unitPeripherally inserted central catheterTrans-pulmonary thermodilution

Identifiers

PMID33284392
PMCPMC7720030

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.