Evidence map›Paper›PMID 33284324›Full record

ArticleJAMA internal medicine2021

Euthanasia and Physician-Assisted Suicide in Patients With Multiple Geriatric Syndromes.

Vera van den Berg, Ghislaine van Thiel, Margot Zomers, Iris Hartog, Carlo Leget, Alfred Sachs, Cuno Uiterwaal, Els van Wijngaarden

Open access · hybridAbstract read
In one paragraph

Article in JAMA internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. [Ageism "in the mind" as a risk factor for suicidal ideation in old age].Zeitschrift fur Gerontologie und Geriatrie · 2025
    Review
  5. Article
  6. Article
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  8. Article
  9. Article
  10. Article
  11. Considerations for assessing frail older adults requesting medical assistance in dying.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Vera van den BergDepartment of Care Ethics, University of Humanistic Studies, Utrecht, the Netherlands.
Ghislaine van ThielDepartment of Medical Humanities, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.
Margot ZomersDepartment of Medical Humanities, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.
Iris HartogDepartment of Medical Ethics, Philosophy, and History of Medicine, Erasmus Medical Center Rotterdam, Rotterdam, the Netherlands.
Carlo LegetDepartment of Care Ethics, University of Humanistic Studies, Utrecht, the Netherlands.
Alfred SachsJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.
Cuno UiterwaalDepartment of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.
Els van WijngaardenDepartment of Care Ethics, University of Humanistic Studies, Utrecht, the Netherlands.
University Medical Center Utrecht · NLUniversity of Humanistic Studies · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Importance: The Dutch Regional Euthanasia Review Committees (RTEs) reviewed and reported an increasing number of cases of euthanasia and physician-assisted suicide (EAS) requested by older people with multiple geriatric syndromes (MGS). Knowledge of the characteristics of cases of EAS for MGS is important to facilitate societal debate and to monitor EAS practice. Objective: To examine the accumulation of patient characteristics, geriatric syndromes, and other circumstances as reported in the case summaries of the RTEs that led to unbearable suffering associated with a request for EAS and to analyze the RTEs' assessments of these cases of EAS. Design, Setting, and Participants: A qualitative content analysis was conducted of all case summaries filed from January 1, 2013, to December 31, 2019, under the category MGS and published in a national open access database. These case summaries were selected by the RTEs from the total of 1605 reported cases of EAS in the category MGS. Results: The RTEs published 53 cases (41 [77%] female) under the category MGS. A total of 28 patients (53%) had always perceived themselves as independent, active, and socially involved. None of the patients suffered from life-threatening conditions. Multiple geriatric syndromes, such as visual impairment (34 cases [64%]), hearing loss (28 cases [53%]), pain (25 cases [47%]), and chronic tiredness (22 cases [42%]), were common. The request for EAS was often preceded by a sequence of events, especially recurrent falls (33 cases [62%]). Although physical suffering could be determined in all cases, the case descriptions found that suffering occurred on multiple dimensions, such as the loss of mobility (44 [83%]), fears (21 [40%]), dependence (23 [43%]), and social isolation (19 [36%]). Conclusions and Relevance: This qualitative study suggests that an accumulation of geriatric syndromes leading to a request for EAS is often intertwined with the social and existential dimension of suffering. This leads to a complex interplay of physical, psychological, and existential suffering that changes over time.

Indexed as

Accidental FallsAged, 80 and overEuthanasiaFemaleHumansMaleMobility LimitationMultiple Chronic ConditionsNetherlandsPersons with DisabilitiesSocial IsolationSuicide, Assisted

Identifiers

PMID33284324
PMCPMC7851730
OpenAlexW3110912641

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.