Evidence map›Paper›PMID 33284108›Full record

ArticleeLife2020

TrpML-mediated astrocyte microdomain Ca

Zhiguo Ma, Marc R Freeman

Abstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. CaActa physiologica (Oxford, England) · 2025
    Article
  9. Article
  10. Glial Regulation of Circuit Wiring, Firing, and Expiring in theCold Spring Harbor perspectives in biology · 2024
    Review
  11. Review
  12. Article
  13. Glia as Functional Barriers and Signaling Intermediaries.Cold Spring Harbor perspectives in biology · 2024
    Review
  14. Article
  15. Evolutionarily conserved concepts in glial cell biology.Current opinion in neurobiology · 2023
    Review
  16. Article
  17. Review
  18. Glial Tiling in the Insect Nervous System.Frontiers in cellular neuroscience · 2022
    Review
  19. Potential and Realized Impact of Astroglia CaFrontiers in cellular neuroscience · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Zhiguo MaVollum Institute, Oregon Health and Science University, Portland, United States.ORCID 0000-0003-2250-1861
Marc R FreemanVollum Institute, Oregon Health and Science University, Portland, United States.ORCID 0000-0003-3481-3715

Funding

The Draper signaling pathway in Drosophila glial immune functionsR01NS053538 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Marc R Freeman · 2006 to 2026
$5.3M
Astrocyte control of neural circuits and behaviorR37NS053538 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI FREEMAN, MARC R · 2016 to 2022
$2.9M
NINDS NIH HHS R01 NS03538NINDS NIH HHS R01 NS053538NINDS NIH HHS R37 NS053538
6 · The paper itself

Abstract

Astrocytes exhibit spatially-restricted near-membrane microdomain Ca

Indexed as

AcetylcholineAction PotentialsAnimalsAstrocytesCalciumCalcium SignalingCentral Nervous SystemDrosophila melanogasterDrosophila ProteinsEnzyme Inhibitorsgamma-Aminobutyric AcidGene Expression RegulationLanthanumMembrane MicrodomainsMutationReactive Oxygen SpeciesAcetylcholineCalciumDrosophila ProteinsEnzyme Inhibitorsgamma-Aminobutyric AcidLanthanumlanthanum chlorideReactive Oxygen SpeciesReceptors, Biogenic AmineTetrodotoxinTransient Receptor Potential ChannelsTRPML protein, DrosophilaTyraminetyramine receptorastrocytecalcium transientcalcium transientsD. melanogasterDrosophilaglianeuron-glia signalingneuroscience

Identifiers

PMID33284108
PMCPMC7721441

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.