Evidence map›Paper›PMID 33284105›Full record

ArticleeLife2020

Co-movement of astral microtubules, organelles and F-actin by dynein and actomyosin forces in frog egg cytoplasm.

James F Pelletier, Christine M Field, Sebastian Fürthauer, Matthew Sonnett, Timothy J Mitchison

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Article
  3. Motor-Assisted Co-Migration of Intracellular Organelles and Microtubules as a Mechanism for Directed Cargo Transport.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Flow, sense and divide.Nature cell biology · 2025
    Article
  9. Article
  10. Live-cell imaging under centrifugation characterized the cellular force for nuclear centration in theProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Spring-like behavior of cytoplasm holds the mitotic spindle in place.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  20. Contribution of cytoplasm viscoelastic properties to mitotic spindle positioning.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

James F PelletierDepartment of Systems Biology, Harvard Medical School, Boston, United States.ORCID 0000-0001-8064-0259
Christine M FieldDepartment of Systems Biology, Harvard Medical School, Boston, United States.ORCID 0000-0002-6433-7804
Sebastian FürthauerFlatiron Institute, Center for Computational Biology, New York, United States.ORCID 0000-0001-9581-5963
Matthew SonnettDepartment of Systems Biology, Harvard Medical School, Boston, United States.
Timothy J MitchisonDepartment of Systems Biology, Harvard Medical School, Boston, United States.ORCID 0000-0001-7781-1897
Marine Biological Laboratory · USFlatiron Health (United States) · USHarvard University · US

Funding

Cell and Chemical Biology of MicrotubulesR35GM131753 · NIGMS · HARVARD MEDICAL SCHOOL · PI Timothy J Mitchison · 2019 to 2026
$6.4M
NIGMS NIH HHS R35 GM131753
6 · The paper itself

Abstract

How bulk cytoplasm generates forces to separate post-anaphase microtubule (MT) asters in

Indexed as

ActinsActomyosinAnimalsCytokinesisCytoplasmDyneinsFemaleMicrotubulesOocytesOrganellesXenopus laevisActinsActomyosinDyneinsactincell biologycytoplasmdyneinERmechanicsmicrotubulephysics of living systemsxenopus

Identifiers

PMID33284105
PMCPMC7759381
OpenAlexW3112872934

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.