ReviewAmerican journal of physiology. Endocrinology and metabolism2021
Gut-to-brain signals in feeding control.
Review in American journal of physiology. Endocrinology and metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 38 citations in OpenAlex.
- Bifidobacterium longum and prebiotic interventions restore early-life high-fat/high-sugar diet-induced alterations in feeding behavior in adult mice.Nature communications · 2026Article
- Obesity and Gut-Brain Communication: The Cholinergic-Endocannabinoid Link.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Obesity- and diet-induced plasticity in systems that control eating and energy balance.Obesity (Silver Spring, Md.) · 2024Review
- Motilin, a Novel Orexigenic Factor, Involved in Feeding Regulation in Yangtze Sturgeon (Biomolecules · 2024Article
- The hypothalamus as the central regulator of energy balance and its impact on current and future obesity treatments.Archives of endocrinology and metabolism · 2024Review
- Review
- High sucrose consumption decouples intrinsic and synaptic excitability of AgRP neurons without altering body weight.International journal of obesity (2005) · 2023Article
- Fatty Acid Sensing in the Gastrointestinal Tract of Rainbow Trout: Different to Mammalian Model?International journal of molecular sciences · 2023Article
- Gut Factors Mediating the Physiological Impact of Bariatric Surgery.Current diabetes reports · 2022Review
- Shedding light on biological sex differences and microbiota-gut-brain axis: a comprehensive review of its roles in neuropsychiatric disorders.Biology of sex differences · 2022Review
- Surrogate fostering of mice prevents prenatal estradiol-induced insulin resistanceFrontiers in microbiology · 2022Article
- Evidence that resistin acts on the mechanical responses of the mouse gastric fundus.Frontiers in physiology · 2022Article
- Article
- Roles for the gut microbiota in regulating neuronal feeding circuits.The Journal of clinical investigation · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Interoceptive signals from gut and adipose tissue and sensory cues from the environment are integrated by hubs in the brain to regulate feeding behavior and maintain homeostatic control of body weight. In vivo neural recordings have revealed that these signals control the activity of multiple layers of hunger neurons and eating is not only the result of feedback correction to a set point, but can also be under the influence of anticipatory regulations. A series of recent technical developments have revealed how peripheral and sensory signals, in particular, from the gut are conveyed to the brain to integrate neural circuits. Here, we describe the mechanisms involved in gastrointestinal stimulation by nutrients and how these signals act on the hindbrain to generate motivated behaviors. We also consider the organization of multidirectional intra- and extrahypothalamic circuits and how this has created a framework for understanding neural control of feeding.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.