Evidence map›Paper›PMID 33284037›Full record

Trial reportClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

Prospective Assessment of Biomarkers of Hypercoagulability for the Identification of Patients With Severe Coronary Artery Disease. The ROADMAP-CAD Study.

Grigoris T Gerotziafas, Theodoros Zografos, Ioannis Pantos, Eleftheria Lefkou, Audrey Carlo, Jawed Fareed, Patrick Van Dreden, Demosthenes Katritsis

Abstract readClinical Trial
In one paragraph

Trial report in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Impact of Dual Antithrombotic Therapy with Aspirin and Rivaroxaban on Secondary Cardiovascular Outcomes.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Grigoris T GerotziafasSorbonne Université, 27102INSERM UMR_938 Cancer Biology and T, Centre de Recherche Saint-Antoine, Institut Universitaire de Cancérologie, Paris, France.ORCID https://orcid.org/0000-0003-2316-6348
Theodoros Zografos3 rd Cardiology Clinic, Hygeia Hospital, Hellenic Healthcare Group, Athens, Greece.
Ioannis PantosRadiology Department, "Amalia Flemig" General Hospital, Melissia, Greece.
Eleftheria LefkouSorbonne Université, 27102INSERM UMR_938 Cancer Biology and T, Centre de Recherche Saint-Antoine, Institut Universitaire de Cancérologie, Paris, France.
Audrey Carlo33289Diagnostica Stago, Gennevilliers, France.
Jawed FareedDepartment of Pathology, Cardiovascular Institute 2456Loyola University Chicago, Maywood, IL, USA.ORCID https://orcid.org/0000-0003-3465-2499
Patrick Van DredenClinical Research Department, 33289Diagnostica Stago, Gennevilliers, France.
Demosthenes Katritsis3 rd Cardiology Clinic, Hygeia Hospital, Hellenic Healthcare Group, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In patients with stable coronary artery disease (CAD) blood hypercoagulability figures among factors leading to thrombosis. Tissue factor (TF) exposure at ruptured plaque initiates blood coagulation and hypercoagulability is responsible for thrombus formation. Early identification of patients eligible for angiography is a challenging issue for effective prevention of ACS. This pilot study aimed to identify biomarkers of hypercoagulability that can be prospectively used in risk assessment tools for the evaluation of CAD severity. Biomarkers of hypercoagulability could be a used for the evaluation of CAD severity. Platelet-poor plasma from 66 patients who were referred to coronary angiography was assessed for thrombin generation, phospholipid-dependent clotting time

Indexed as

AgedBiomarkersBlood CoagulationBlood Coagulation TestsCoronary Artery DiseaseFemaleFibrin Fibrinogen Degradation ProductsHumansMaleMiddle AgedPilot ProjectsProspective StudiesRisk AssessmentThrombophiliaBiomarkersFibrin Fibrinogen Degradation Productsfibrin fragment Dcoronary artery diseaseprocoagulant phospholipidsrisk assessment modelthrombin generation

Identifiers

PMID33284037
PMCPMC7724406

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.