Evidence map›Paper›PMID 33284012›Full record

ArticleACS chemical neuroscience2020

Synthesis and Autoradiography of Novel F-18 Labeled Reversible Radioligands for Detection of Monoamine Oxidase B.

Sangram Nag, Zhisheng Jia, Marie Svedberg, Alex Jackson, Rabia Ahmad, Sajinder Luthra, Katarina Varnäs, Lars Farde, Christer Halldin

Open access · hybridAbstract read
In one paragraph

Article in ACS chemical neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Development and evaluation of a novel deuterated fluorine-18 PET tracer for MAO-B imaging.American journal of nuclear medicine and molecular imaging · 2026
    Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Sangram NagDepartment of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet and Stockholm County Council, Stockholm 17176, Sweden.ORCID 0000-0003-3590-4256
Zhisheng JiaDepartment of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet and Stockholm County Council, Stockholm 17176, Sweden.
Marie SvedbergDepartment of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet and Stockholm County Council, Stockholm 17176, Sweden.
Alex JacksonGE Healthcare Pharmaceutical Diagnostics, Little Chalfont HP8 4SP, United Kingdom.
Rabia AhmadGE Healthcare Pharmaceutical Diagnostics, Little Chalfont HP8 4SP, United Kingdom.
Sajinder LuthraGE Healthcare Pharmaceutical Diagnostics, Little Chalfont HP8 4SP, United Kingdom.
Katarina VarnäsDepartment of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet and Stockholm County Council, Stockholm 17176, Sweden.
Lars FardeDepartment of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet and Stockholm County Council, Stockholm 17176, Sweden.
Christer HalldinDepartment of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet and Stockholm County Council, Stockholm 17176, Sweden.
Stockholm County Council · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monoamine oxidase B (MAO-B) is an important enzyme regulating the levels of monoaminergic neurotransmitters. Selective MAO-B inhibitors have been labeled with carbon-11 or fluorine-18 to visualize the localization of MAO-B

Indexed as

Fluorine RadioisotopesMonoamine OxidaseAutoradiographyBrainCarbon RadioisotopesHumansMonoamine Oxidase InhibitorsPositron-Emission TomographyRadiopharmaceuticalsCarbon RadioisotopesFluorine RadioisotopesMonoamine OxidaseMonoamine Oxidase InhibitorsRadiopharmaceuticalsautoradiographyfluorine-18MAO-BPETreversible radioligands

Identifiers

PMID33284012
PMCPMC7747220
OpenAlexW3111742328

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.