Evidence map›Paper›PMID 33283559›Full record

ArticleJournal of the American Heart Association2020

Cardiometabolic Risk Factors and Preclinical Target Organ Damage Among Adults in Ghana: Findings From a National Study.

Jie Li, Isaac Kofi Owusu, Qingshan Geng, Aba Ankomaba Folson, Zhichao Zheng, Yaw Adu-Boakye, Xinran Dong, Wen-Chih Wu, Francis Agyekum, Hongwen Fei and 10 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Blood pressure variability and target organ damage regression in hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 6 institutions in 3 countries.

Jie LiGlobal Health Research Center Guangdong Provincial People's HospitalGuangdong Academy of Medical Sciences Guangzhou China.
Isaac Kofi OwusuDepartment of Medicine School of Medicine and Dentistry College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana.
Qingshan GengGuangdong Provincial Key Laboratory of Coronary Heart Disease Prevention Department of Cardiology Guangdong Cardiovascular Institute Guangdong Provincial People's HospitalGuangdong Academy of Medical Sciences Guangzhou China.
Aba Ankomaba FolsonDepartment of Medicine Greater Accra Regional Hospital Accra Ghana.
Zhichao ZhengGuangdong Provincial Key Laboratory of Coronary Heart Disease Prevention Division of Adult Echocardiography Department of Cardiology Guangdong Cardiovascular Institute Guangdong Provincial People's HospitalGuangdong Academy of Medical Sciences Guangzhou China.
Yaw Adu-BoakyeDepartment of Medicine Komfo Anokye Teaching Hospital Kumasi Ghana.
Xinran DongDepartment of Ophthalmology Guangdong Eye Institute Guangdong Provincial People's Hospital Guangdong Academy of Medical Sciences Guangzhou China.
Wen-Chih WuDepartment of Epidemiology and Center for Global Cardiometabolic Health School of Public Health Departments of Medicine and Surgery The Warren Alpert School of MedicineBrown University Providence RI.
Francis AgyekumDepartment of Medicine Greater Accra Regional Hospital Accra Ghana.
Hongwen FeiGuangdong Provincial Key Laboratory of Coronary Heart Disease Prevention Division of Adult Echocardiography Department of Cardiology Guangdong Cardiovascular Institute Guangdong Provincial People's HospitalGuangdong Academy of Medical Sciences Guangzhou China.
Harold AyeteyDepartment of Internal Medicine and Therapeutics School of Medical Sciences University of Cape Coast Ghana.
Mulan DengDepartment of Epidemiology Guangdong Provincial People's Hospital Guangdong Academy of Medical Sciences Guangzhou China.
Fred Adomako-BoatengRegional Directorate of Health Ghana Health Service Ashanti Region, Kumasi Ghana.
Zuxun JiangGuangdong Provincial Key Laboratory of Coronary Heart Disease Prevention Division of Adult Echocardiography Department of Cardiology Guangdong Cardiovascular Institute Guangdong Provincial People's HospitalGuangdong Academy of Medical Sciences Guangzhou China.
Braimah Baba AbubakariRegional Directorate of Health Ghana Health Service Northern Region, Tamale Ghana.
Zhao XianDepartment of Science and Education The Second People's Hospital of Nanhai DistrictGuangdong Provincial People's Hospital's Nanhai Hospital Foshan China.
Forster Nketiah FokuohDepartment of Medicine East Regional Hospital Accra Ghana.
Lambert Tetteh AppiahDepartment of Medicine Komfo Anokye Teaching Hospital Kumasi Ghana.
Simin LiuDepartment of Epidemiology and Center for Global Cardiometabolic Health School of Public Health Departments of Medicine and Surgery The Warren Alpert School of MedicineBrown University Providence RI.
Chunying LinGuangdong Provincial Key Laboratory of Coronary Heart Disease Prevention Department of Cardiology Guangdong Cardiovascular Institute Guangdong Provincial People's HospitalGuangdong Academy of Medical Sciences Guangzhou China.
Guangdong Academy of Medical Sciences · CNGhana Health Service · GHBrown University · USKomfo Anokye Teaching Hospital · GHFoshan Second People's Hospital · CNUniversity of Cape Coast · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Although sub-Saharan Africa has a high prevalence of cardiovascular diseases (CVDs), there remains a lack of systematic and comprehensive assessment of risk factors and early CVD outcomes in adults in sub-Saharan Africa. Methods and Results Using a stratified multistage random sampling method, we recruited 1106 men and women, aged >18 years, from the general population in Ghana to participate in a national health survey from 2016 to 2017. In Ghanaian adults, the age-standardized prevalence of known CVD risk factors was 15.1% (95% CI, 12.9%-17.3%) for obesity, 6.8% (95% CI, 5.1%-8.5%) for diabetes mellitus, 26.1% (95% CI, 22.9%-29.4%) for hypertension, and 9.3% (95% CI, 7.1%-11.5%) for hyperuricemia. In addition, 10.1% (95% CI, 7.0%-13.2%) of adults had peripheral artery disease, 8.3% (95% CI, 6.7%-10.0%) had carotid thickening, 4.1% (95% CI, 2.9%-5.2%) had left ventricular hypertrophy, and 2.5% (95% CI, 1.5%-3.4%) had chronic kidney disease. Three CVD risk factors appeared to play prominent roles in the development of target organ damage, including obesity for peripheral artery disease (odds ratio [OR], 2.22; 95% CI, 1.35-3.63), hypertension for carotid thickening (OR, 1.92; 95% CI, 1.22-3.08), and left ventricular hypertrophy (OR, 5.28; 95% CI, 2.55-12.11) and hyperuricemia for chronic kidney disease (OR, 5.49; 95% CI, 2.84-10.65). Conclusions This comprehensive health survey characterized the baseline conditions of a national cohort of adults while confirming the prevalence of CVD risk factors, and early CVD outcomes have reached epidemic proportions in Ghana. The distinct patterns of risk factors in the development of target organ damage present important challenges and opportunities for interventions to improve cardiometabolic health among adults in Ghana.

Indexed as

Cardiometabolic Risk FactorsAdultCardiovascular DiseasesCase-Control StudiesCross-Sectional StudiesDiabetes MellitusFemaleGhanaHealth SurveysHumansHypertensionHyperuricemiaMaleMiddle AgedMultiple Organ FailureObesityadultscardiovascular diseaseGhanarisk factorstarget organ damage

Identifiers

PMID33283559
PMCPMC7955390
OpenAlexW3113229506

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.