ArticleClinical and experimental dental research2021
Bioactive glass versus Arginine dentifrices on the reduction of dentin permeability and acid tolerance.
Article in Clinical and experimental dental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Adjunctive effect of dentifrices on the durability of in-office desensitizing treatment under erosive-abrasive conditions.BMC oral health · 2026Article
- Short-term effectiveness of three agents for dentin hypersensitivity treatment: A randomized clinical trial.Bioinformation · 2026Article
- Bioactive glass products for the treatment of dentin hypersensitivity: a scoping review.Clinical oral investigations · 2025Article
- Article
- Effectiveness of a Single Chair Side Application of NovaMinMaterials (Basel, Switzerland) · 2023Article
- Bioactive glass versus Arginine dentifrices on the reduction of dentin permeability and acid tolerance.Clinical and experimental dental research · 2021Article
- Comparative Study on the Efficacy of OliNano Seal and Curodont D'Senz in the Treatment of Dentin Hypersensitivity (Clinical Trial andJournal of International Society of Preventive & Community DentistryArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
objectivesTo compare the efficacy of calcium sodium phosphosilicate (CSPS) and arginine dentifrices on dentin permeability and acid tolerance. MATERIAL AND
methodsSixty dentin discs were randomly assigned into 3 groups, then brushed for 1 min with CSPS, arginine, or fluoride (control) dentifrices. To test acid tolerance, each disc was soaked in 6% citric acid for 1 min. Dentin permeability was measured before, following brushing, and acid challenge. Ten discs per group were similarly treated and evaluated for tubule occlusion following a single dentifrice application, while other five discs per group were employed in an acid tolerance assay.
resultsThe percentage reduction in dentin permeability was 39.26%, 32.27%, and 21.71% in the arginine, CSPS, and control groups, respectively. The differences in dentin permeability reduction between the arginine and CSPS groups following brushing and acid challenge were not significant (p = 0.398 and p = 0.211, respectively). The arginine dentifrice demonstrated a significant reduction in permeability compared with the control (p = 0.011). In addition, the occlusion exhibited by the arginine and CSPS dentifrices was more resistant to acid challenge compared with that of the control (p < 0.001). From SEM analysis, dentinal tubule occlusion was observed after a single application in all groups. Some open dentinal tubules were detected in the test groups, while almost all of the orifices were open in the fluoride group following acid challenge.
conclusionsThere is no significant difference between arginine and CSPS dentifrices in reducing dentin permeability following a single application and acid challenge. Following acid challenge, the reduced permeability generated by arginine and CSPS was more stable compared with the fluoride dentifrice.
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