Evidence map›Paper›PMID 33283395›Full record

ArticleAngewandte Chemie (International ed. in English)2021

Embedment of Quantum Dots and Biomolecules in a Dipeptide Hydrogel Formed In Situ Using Microfluidics.

Yue Li, Max J Männel, Nicolas Hauck, Himanshu P Patel, Günter K Auernhammer, Soosang Chae, Andreas Fery, Junbai Li, Julian Thiele

Open access · greenAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Yue LiLeibniz-Institut für Polymerforschung Dresden e.V., 01069, Dresden, Germany.ORCID 0000-0002-9787-2264
Max J MännelLeibniz-Institut für Polymerforschung Dresden e.V., 01069, Dresden, Germany.
Nicolas HauckLeibniz-Institut für Polymerforschung Dresden e.V., 01069, Dresden, Germany.
Himanshu P PatelLeibniz-Institut für Polymerforschung Dresden e.V., 01069, Dresden, Germany.
Günter K AuernhammerLeibniz-Institut für Polymerforschung Dresden e.V., 01069, Dresden, Germany.ORCID 0000-0003-1515-0143
Soosang ChaeLeibniz-Institut für Polymerforschung Dresden e.V., 01069, Dresden, Germany.
Andreas FeryLeibniz-Institut für Polymerforschung Dresden e.V., 01069, Dresden, Germany.ORCID 0000-0001-6692-3762
Junbai LiBeijing National Laboratory for Molecular Sciences (BNLMS), CAS Key Laboratory of Colloids, Interface and Chemical, Thermodynamics, Institute of Chemistry, Chinese Academy of Sciences, 100190, Beijing, China.ORCID 0000-0001-9575-3125
Julian ThieleLeibniz-Institut für Polymerforschung Dresden e.V., 01069, Dresden, Germany.ORCID 0000-0001-5449-3048
Leibniz Institute of Polymer Research · DEChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As low-molecular-weight hydrogelators, dipeptide hydrogel materials are suited for embedding multiple organic molecules and inorganic nanoparticles. Herein, a simple but precisely controllable method is presented that enables the fabrication of dipeptide-based hydrogels by supramolecular assembly inside microfluidic channels. Water-soluble quantum dots (QDs) as well as premixed porphyrins and a dipeptide in dimethyl sulfoxide (DMSO) were injected into a Y-shaped microfluidic junction. At the DMSO/water interface, the confined fabrication of a dipeptide-based hydrogel was initiated. Thereafter, the as-formed hydrogel flowed along a meandering microchannel in a continuous fashion, gradually completing gelation and QD entrapment. In contrast to hydrogelation in conventional test tubes, microfluidically controlled hydrogelation led to a tailored dipeptide hydrogel regarding material morphology and nanoparticle distribution.

Indexed as

continuous-flow microfluidicsdipeptidesmicrochannel-confined assemblynanostructuressupramolecular assembly

Identifiers

PMID33283395
PMCPMC7986802
OpenAlexW3130173000

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.