Evidence map›Paper›PMID 33283381›Full record

ArticleJournal of magnetic resonance imaging : JMRI2021

Comparison Between Diffusion-Weighted MRI and

Laura Privitera, Patrick W Hales, Layla Musleh, Elizabeth Morris, Natalie Sizer, Giuseppe Barone, Paul Humphries, Kate Cross, Lorenzo Biassoni, Stefano Giuliani

Open access · hybridAbstract read
In one paragraph

Article in Journal of magnetic resonance imaging : JMRI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Prognostic value of baseline [68Ga]Ga‑DOTA‑NOC PET/CT in paediatric neuroblastoma.European journal of nuclear medicine and molecular imaging · 2026
    Article
  3. Review
  4. The value ofFrontiers in medicine · 2025
    Article
  5. Review
  6. Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Laura PriviteraDepartment of Specialist Neonatal and Paediatric Surgery, Great Ormond Street Hospital for Children, London, UK.ORCID 0000-0002-6384-6367
Patrick W HalesDevelopmental Imaging and Biophysics Section, University College London Great Ormond Street Insitute of Child Health, London, UK.ORCID 0000-0002-4269-0252
Layla MuslehDepartment of Specialist Neonatal and Paediatric Surgery, Great Ormond Street Hospital for Children, London, UK.
Elizabeth MorrisDepartment of Radiology, Great Ormond Street Hospital for Children, London, UK.
Natalie SizerDepartment of Radiology, Great Ormond Street Hospital for Children, London, UK.
Giuseppe BaroneDepartment of Haematology and Oncology, Great Ormond Street Hospital for Children, London, UK.
Paul HumphriesDepartment of Radiology, Great Ormond Street Hospital for Children, London, UK.
Kate CrossDepartment of Specialist Neonatal and Paediatric Surgery, Great Ormond Street Hospital for Children, London, UK.
Lorenzo BiassoniDepartment of Radiology, Great Ormond Street Hospital for Children, London, UK.
Stefano GiulianiDepartment of Specialist Neonatal and Paediatric Surgery, Great Ormond Street Hospital for Children, London, UK.
Great Ormond Street Hospital · GBBarts Health NHS Trust · GB

Funding

Medical Research Council MR/T005491/1Wellcome Trust
6 · The paper itself

Abstract

backgroundHigh-risk neuroblastoma (HR-NB) has a variable response to preoperative chemotherapy. It is not possible to differentiate viable vs. nonviable residual tumor before surgery. PURPOSE: To explore the association between apparent diffusion coefficient (ADC) values from diffusion-weighted magnetic resonance imaging (DW-MRI), STUDY TYPE: Retrospective. SUBJECTS: Forty patients with HR-NB. FIELD STRENGTH/SEQUENCE: 1.5T axial DW-MRI (b = 0,1000 s/mm ASSESSMENT: ADC maps and STATISTICAL TESTS: Analysis of variance (ANOVA) and linear regression were used to compare ADC and MIBG values before and after treatment. Threshold values to classify tumors as viable/necrotic were obtained using ROC analysis of ADC and TLCR values.

resultsNo significant difference in whole-tumor ADC LEVEL OF EVIDENCE: 4. TECHNICAL EFFICACY STAGE: 3.

Indexed as

Diffusion Magnetic Resonance ImagingNeuroblastoma3-IodobenzylguanidineHumansRetrospective StudiesTumor Burden3-Iodobenzylguanidine123I-mIBG uptakeapparent diffusion coefficientdiffusion weighted-imaginghigh-risk neuroblastomahistopathology

Identifiers

PMID33283381
PMCPMC8246892
OpenAlexW3113327466

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.