Evidence map›Paper›PMID 33283008›Full record

ReviewOrthopaedic journal of sports medicine2020

Platelet-Rich Plasma Augmentation for Isolated Arthroscopic Meniscal Repairs Leads to Significantly Lower Failure Rates: A Systematic Review of Comparative Studies.

Kyle R Sochacki, Marc R Safran, Geoffrey D Abrams, Joseph Donahue, Constance Chu, Seth L Sherman

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Orthopaedic journal of sports medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Efficacy of platelet-rich plasma in meniscal repair surgery: a systematic review of randomized controlled trials.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2024
    Pooled it
  2. Pooled it
  3. Platelet-rich plasma (PRP) augmentation does not result in more favourable outcomes in arthroscopic meniscal repair: a meta-analysis.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2022
    Pooled it
  4. Trial
  5. Trial
  6. Review
  7. Article
  8. Article
  9. Biologic Augmentation for Meniscus Repair: A Narrative Review.Bioengineering (Basel, Switzerland) · 2026
    Review
  10. Article
  11. Management of Horizontal Cleavage Meniscus Tears.Current reviews in musculoskeletal medicine · 2025
    Review
  12. Review
  13. Review
  14. Biologic Augmentation of Isolated Meniscal Repair.Current reviews in musculoskeletal medicine · 2024
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Biomaterials for Interbody Fusion in Bone Tissue Engineering.Frontiers in bioengineering and biotechnology · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kyle R SochackiDepartment of Orthopaedic Surgery, Stanford University Medical Center, Palo Alto, California, USA.
Marc R SafranDepartment of Orthopaedic Surgery, Stanford University Medical Center, Palo Alto, California, USA.
Geoffrey D AbramsDepartment of Orthopaedic Surgery, Stanford University Medical Center, Palo Alto, California, USA.
Joseph DonahueDepartment of Orthopaedic Surgery, Stanford University Medical Center, Palo Alto, California, USA.
Constance ChuDepartment of Orthopaedic Surgery, Stanford University Medical Center, Palo Alto, California, USA.
Seth L ShermanDepartment of Orthopaedic Surgery, Stanford University Medical Center, Palo Alto, California, USA.
Stanford Medicine · USStanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies have reported relatively high failure rates of isolated meniscal repairs. Platelet-rich plasma (PRP) has been suggested as a way to increase growth factors that enhance healing. PURPOSE: To compare (1) meniscal repair failures and (2) patient-reported outcomes after isolated arthroscopic meniscal repair augmented with and without PRP. STUDY

designSystematic review; Level of evidence, 3.

methodsA systematic review was performed using the PRISMA (Preferred Reporting Items for Systematic Meta-Analyses) guidelines. Multiple databases were searched for studies that compared outcomes of isolated arthroscopic meniscal repair augmented with PRP versus without PRP in human patients. Failures and patient-reported outcome scores were reported for each study and compared between groups. Study heterogeneity was assessed using

resultsFive articles were analyzed (274 patients [110 with PRP and 164 without PRP]; 65.8% male; mean age, 29.1 ± 4.6 years; mean follow-up, 29.2 ± 22.1 months). The risk of meniscal repair failure ranged from 4.4% to 26.7% for PRP-augmented repairs and 13.3% to 50.0% for repairs without PRP. Meniscal repairs augmented with PRP had significantly lower failure rates than repairs without PRP (odds ratio, 0.32; 95% CI, 0.12-0.90;

conclusionAlthough the studies were of mostly of low quality, isolated arthroscopic meniscal repairs augmented with PRP led to significantly lower failure rates (10.8% vs 27.0%; odds ratio, 0.32;

Indexed as

failuresmeniscal repairplatelet-rich plasmaPRP

Identifiers

PMID33283008
PMCPMC7682240
OpenAlexW3108611029

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.