Evidence map›Paper›PMID 33282910›Full record

ArticleFrontiers in molecular biosciences2020

Versatile Role of Rab27a in Glioma: Effects on Release of Extracellular Vesicles, Cell Viability, and Tumor Progression.

Thomas S van Solinge, Erik R Abels, Lieke L van de Haar, Killian S Hanlon, Sybren L N Maas, Rosalie Schnoor, Jeroen de Vrij, Xandra O Breakefield, Marike L D Broekman

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Effects of a GlobalArteriosclerosis, thrombosis, and vascular biology · 2024
    Article
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  5. Article
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  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Thomas S van SolingeDepartment of Neurology and Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Erik R AbelsDepartment of Neurology and Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Lieke L van de HaarDepartment of Neurology and Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Killian S HanlonDepartment of Neurobiology, Harvard Medical School, Boston, MA, United States.
Sybren L N MaasDepartment of Neurosurgery, UMC Utrecht Brain Center, Utrecht University, Utrecht, Netherlands.
Rosalie SchnoorDepartment of Neurosurgery, UMC Utrecht Brain Center, Utrecht University, Utrecht, Netherlands.
Jeroen de VrijDepartment of Neurosurgery, Brain Tumor Center, Erasmus Medical Center, Rotterdam, Netherlands.
Xandra O BreakefieldDepartment of Neurology and Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Marike L D BroekmanDepartment of Neurology and Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Harvard University · USMassachusetts General Hospital · USUtrecht University · NL

Funding

The role of microvesicles in giloma virotherapyP01CA069246 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI CHAREST, ALAIN · 1996 to 2021
$30.9M
Transfer of microRNA regulators from glioblastoma to brain microenvironment U19CA179563 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI BREAKEFIELD, XANDRA OWENS, CHAREST, ALAIN · 2013 to 2017
$8.6M
The power of extracellular vesicles in glioblastomaR35CA232103 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI BREAKEFIELD, XANDRA OWENS · 2018 to 2024
$6.9M
NCI NIH HHS P01 CA069246NCI NIH HHS R35 CA232103NCI NIH HHS U19 CA179563
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

exosomesextracellular vesiclesglioblastomagliomaRab27atumor microenvironment

Identifiers

PMID33282910
PMCPMC7691322
OpenAlexW3100274074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.