Evidence map›Paper›PMID 33282795›Full record

ReviewClinical and translational imaging2020

Diffusion tensor imaging of the roots of the brachial plexus: a systematic review and meta-analysis of normative values.

Ryckie G Wade, Alexander Whittam, Irvin Teh, Gustav Andersson, Fang-Cheng Yeh, Mikael Wiberg, Grainne Bourke

Open access · hybridAbstract readReview
In one paragraph

Review in Clinical and translational imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Magnetic resonance tractography of the brachial plexus: step-by-step.Quantitative imaging in medicine and surgery · 2022
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Ryckie G WadeDepartment of Plastic and Reconstructive Surgery, Leeds Teaching Hospitals Trust, Leeds, LS1 3EX UK.ORCID 0000-0001-8365-6547
Alexander WhittamSheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Irvin TehLeeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.ORCID 0000-0002-6705-3129
Gustav AnderssonDepartment of Integrative Medical Biology, Faculty of Medicine, Umeå University, Umeå, Sweden.ORCID 0000-0002-9925-4224
Fang-Cheng YehDepartment of Neurological Surgery, University of Pittsburgh, Pittsburgh, USA.ORCID 0000-0002-7946-2173
Mikael WibergDepartment of Integrative Medical Biology, Faculty of Medicine, Umeå University, Umeå, Sweden.ORCID 0000-0002-1476-3952
Grainne BourkeDepartment of Plastic and Reconstructive Surgery, Leeds Teaching Hospitals Trust, Leeds, LS1 3EX UK.ORCID 0000-0003-0059-8543
University of Leeds · GBUmeå University · SESheffield Teaching Hospitals NHS Foundation Trust · GBUniversity of Pittsburgh · US

Funding

Department of Health DRF-2018-11-ST2-028
6 · The paper itself

Abstract

purposeDiffusion tensor magnetic resonance imaging (DTI) characterises tissue microstructure and provides proxy measures of myelination, axon diameter, fibre density and organisation. This may be valuable in the assessment of the roots of the brachial plexus in health and disease. Therefore, there is a need to define the normal DTI values.

methodsThe literature was systematically searched for studies of asymptomatic adults who underwent DTI of the brachial plexus. Participant characteristics, scanning protocols, and measurements of the fractional anisotropy (FA) and mean diffusivity (MD) of each spinal root were extracted by two independent review authors. Generalised linear modelling was used to estimate the effect of experimental conditions on the FA and MD. Meta-analysis of root-level estimates was performed using Cohen's method with random effects.

resultsNine articles, describing 316 adults (1:1 male:female) of mean age 35 years (SD 6) were included. Increments of ten diffusion sensitising gradient directions reduced the mean FA by 0.01 (95% CI 0.01, 0.03). Each year of life reduced the mean MD by 0.03 × 10

conclusionsThe FA and MD of the roots of the brachial plexus vary according to experimental conditions and participant factors. We provide summary estimates of the normative values in different conditions which may be valuable to researchers and clinicians alike.

Indexed as

Brachial plexusDiffusion tensorHealthyNormalNormativePeripheral nerve

Identifiers

PMID33282795
PMCPMC7708343
OpenAlexW3092610428

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.