Evidence map›Paper›PMID 33282681›Full record

ArticleAdvanced modeling and simulation in engineering sciences2020

A flexible framework for sequential estimation of model parameters in computational hemodynamics.

Christopher J Arthurs, Nan Xiao, Philippe Moireau, Tobias Schaeffter, C Alberto Figueroa

Abstract read
In one paragraph

Article in Advanced modeling and simulation in engineering sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  6. Review
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  9. Inverse problems in blood flow modeling: A review.International journal for numerical methods in biomedical engineering · 2022
    Review
  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christopher J Arthurs *Dept. of Biomedical Engineering, King's College London, London, UK.ORCID 0000-0002-0448-6146
Nan Xiao *Dept. of Biomedical Engineering, King's College London, London, UK.
Philippe MoireauInria, Inria Saclay-Ile de France, 91128 Palaiseau, France.
Tobias SchaeffterPhysikalisch-Technische Bundesanstalt, Berlin, Germany.
C Alberto FigueroaDepts. of Surgery and Biomedical Engineering, University of Michigan, 2800 Plymouth Rd, Ann Arbor, MI 48109 USA.

Funding

Mechanisms Underlying The Progression of Large Artery Stiffness in HypertensionR01HL105297 · NHLBI · YALE UNIVERSITY · PI FIGUEROA, CARLOS ALBERTO, HUMPHREY, JAY D. · 2010 to 2019
$3.0M
Image-based Multi-scale Modeling Framework of the Cardiopulmonary System: Longitudinal Calibration and Assessment of Therapies in Pediatric Pulmonary HypertensionU01HL135842 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BAEK, SEUNGIK, DORFMAN, ADAM LEE · 2017 to 2020
$2.3M
NHLBI NIH HHS R01 HL105297NHLBI NIH HHS U01 HL135842Wellcome Trust
6 · The paper itself

Abstract

A major challenge in constructing three dimensional patient specific hemodynamic models is the calibration of model parameters to match patient data on flow, pressure, wall motion, etc. acquired in the clinic. Current workflows are manual and time-consuming. This work presents a flexible computational framework for model parameter estimation in cardiovascular flows that relies on the following fundamental contributions. (i) A Reduced-Order Unscented Kalman Filter (ROUKF) model for data assimilation for wall material and simple lumped parameter network (LPN) boundary condition model parameters. (ii) A constrained least squares augmentation (ROUKF-CLS) for more complex LPNs. (iii) A "Netlist" implementation, supporting easy filtering of parameters in such complex LPNs. The ROUKF algorithm is demonstrated using non-invasive patient-specific data on anatomy, flow and pressure from a healthy volunteer. The ROUKF-CLS algorithm is demonstrated using synthetic data on a coronary LPN. The methods described in this paper have been implemented as part of the CRIMSON hemodynamics software package.

Indexed as

Boundary conditionsComputational hemodynamicsData assimilationKalman filteringParameter estimationPatient specific modelingStiffness

Identifiers

PMID33282681
PMCPMC7717067

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.