ArticleBiomedical optics express2020
Space-enhanced time-domain diffuse optics for determination of tissue optical properties in two-layered structures.
Article in Biomedical optics express, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed.
- Monte Carlo-based correction of geometric and instrumental biases in single-distance time-domain near-infrared spectroscopy on skeletal muscle.Biomedical optics express · 2026Article
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- Approaches for modelling autocorrelation function and data processing in time-domain diffuse correlation spectroscopy.Biomedical optics express · 2025Article
- Development of a statistically standardized optical digital wrist model through integrated MRI-diffuse optical imaging methodology.Journal of biomedical optics · 2025Article
- Spectrally-resolved errors in absorption and reduced scattering due toBiomedical optics express · 2025Article
- Noninvasive monitoring of fetal tissue oxygenation level using time-domain NIRS.Journal of biomedical optics · 2025Article
- Evaluation of layered tissue scattering properties: a time-domain spatially resolved spectroscopy approach.Journal of biomedical optics · 2025Article
- Phase-based structured interrogation frequency-domain near-infrared spectroscopy.Journal of the Optical Society of America. A, Optics, image science, and vision · 2024Article
- Statistics of maximum photon penetration depth in a two-layer diffusive medium.Biomedical optics express · 2024Article
- Depth-selective method for time-domain diffuse reflectance measurements: validation study of the dual subtraction technique.Biomedical optics express · 2023Article
- Two-layered blood-lipid phantom and method to determine absorption and oxygenation employing changes in moments of DTOFs.Biomedical optics express · 2023Article
- Multi-laboratory performance assessment of diffuse optics instruments: the BitMap exercise.Journal of biomedical optics · 2022Article
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6 authors.
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Abstract
A novel methodology for solving the inverse problem of diffuse optics for two-layered structures is proposed to retrieve the absolute quantities of optical absorption and reduced scattering coefficients of the layers simultaneously. A liquid phantom with various optical absorption properties in the deep layer is prepared and experimentally investigated using the space-enhanced time-domain method. Monte-Carlo simulations are applied to analyze the different measurements in time domain, space domain, and by the new methodology. The deviations of retrieved values from nominal values of both layers' optical properties are simultaneously reduced to a very low extent compared to the single-domain methods. The reliability and uncertainty of the retrieval performance are also considerably improved by the new methodology. It is observed in time-domain analyses that for the deep layer the retrieval of absorption coefficient is almost not affected by the scattering properties and this kind of "deep scattering neutrality" is investigated and overcome as well.
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