Evidence map›Paper›PMID 33282490›Full record

ArticleBiomedical optics express2020

Portable ultra-widefield fundus camera for multispectral imaging of the retina and choroid.

Devrim Toslak, Taeyoon Son, Muhammet Kazim Erol, Hoonsup Kim, Tae-Hoon Kim, R V Paul Chan, Xincheng Yao

Abstract read
In one paragraph

Article in Biomedical optics express, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Multispectral Fundus Photography of Choroidal Nevi with Trans-Palpebral Illumination.medRxiv : the preprint server for health sciences · 2024
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Emerging imaging developments in experimental vision sciences and ophthalmology.Experimental biology and medicine (Maywood, N.J.) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Devrim ToslakDepartment of Bioengineering, University of Illinois at Chicago, Chicago, IL 60607, USA.
Taeyoon SonDepartment of Bioengineering, University of Illinois at Chicago, Chicago, IL 60607, USA.
Muhammet Kazim ErolAntalya Training and Research Hospital, Department of Ophthalmology, Antalya, 07100, Turkey.
Hoonsup KimDepartment of Bioengineering, University of Illinois at Chicago, Chicago, IL 60607, USA.ORCID https://orcid.org/0000-0002-4391-4860
Tae-Hoon KimDepartment of Bioengineering, University of Illinois at Chicago, Chicago, IL 60607, USA.
R V Paul ChanDepartment of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL 60612, USA.
Xincheng YaoDepartment of Bioengineering, University of Illinois at Chicago, Chicago, IL 60607, USA.ORCID https://orcid.org/0000-0002-0356-3242

Funding

Translational Core for Therapeutic and Diagnostic DevelopmentP30EY001792 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI AAKALU, VINAY · 1985 to 2025
$14.8M
Functional imaging of retinal photoreceptorsR01EY023522 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI YAO, XINCHENG · 2014 to 2024
$3.5M
Nonmydriatic ultra-widefield fundus photography employing trans-pars-planar illuminationR01EY029673 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CHAN, ROBISON VERNON PAUL, YAO, XINCHENG · 2019 to 2022
$1.8M
Differential artery-vein analysis in OCT angiography for objective classification of diabetic retinopathyR01EY030842 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LIM, JENNIFER IRENE, YAO, XINCHENG · 2020 to 2023
$1.7M
Functional tomography of neurovascular coupling interactions in healthy and diseased retinasR01EY030101 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI YAO, XINCHENG · 2019 to 2022
$1.4M
A portable ultra-widefield fundus camera for nonmydriatic examination of retinopathy of prematurityR43EY028786 · NEI · BIOLIGHT ENGINEERING, LLC · PI SON, TAEYUN, YAO, XINCHENG · 2018 to 2018
$233k
NEI NIH HHS P30 EY001792NEI NIH HHS R01 EY023522NEI NIH HHS R01 EY029673NEI NIH HHS R01 EY030101NEI NIH HHS R01 EY030842NEI NIH HHS R43 EY028786
6 · The paper itself

Abstract

Multispectral imaging (MSI) of the retina and choroid has increasing interest for better diagnosis and treatment evaluation of eye diseases. However, currently available MSI systems have a limited field of view (FOV) to evaluate the peripheral retina. This study is to validate trans-pars-planar illumination for a contact-mode ultra-widefield MSI system. By freeing the available pupil for collecting imaging light only, the trans-pars-planar illumination enables a portable, non-mydriatic fundus camera, with 200° FOV in a single fundus image. The trans-pars-planar illumination, delivering illumination light from one side of the eye, naturally enables oblique illumination ophthalmoscopy to enhance the contrast of fundus imaging. A broadband (104 nm) 565 nm light-emitting diode (LED) is used for validating color fundus imaging first. Four narrowband (17-60 nm) 530 nm, 625 nm, 780 nm, and 970 nm LEDs are tested for MSI. With 530 nm illumination, the fundus image reveals retinal vasculature predominantly. 625 nm and 780 nm illuminations enhance the visibility of choroidal vasculature. With further increased wavelength of 970 nm, the fundus image is predominated by large veins in the choroid, with multiple vortex ampullas observed simultaneously in a single fundus image.

Identifiers

PMID33282490
PMCPMC7687931

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.