Evidence map›Paper›PMID 33282466›Full record

ArticleJournal of radiosurgery and SBRT2020

Feasibility of spinal stereotactic body radiotherapy in Elekta Unity

Eun Young Han, Manik Aima, Neil Hughes, Tina M Briere, Debra N Yeboa, Pam Castillo, Jihong Wang, Jinzhong Yang, Sastry Vedam

Abstract read
In one paragraph

Article in Journal of radiosurgery and SBRT, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Eun Young HanDepartment of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Manik AimaDepartment of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Neil HughesDepartment of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Tina M BriereDepartment of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Debra N YeboaDepartment of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Pam CastilloDepartment of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Jihong WangDepartment of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Jinzhong YangDepartment of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Sastry VedamDepartment of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Elekta Unity MR-Linac (MRL) is expected to benefit spine stereotactic body radiotherapy (SBRT) due to the improved soft tissue contrast available with onboard MR imaging. However, the irradiation geometry and beam configuration of the MRL deviates from the conventional linear accelerator (Linac). The purpose of the study was to investigate the feasibility of spine SBRT on the MRL. Treatment plans were generated for lumbar and thoracic spines. Target and spinal cord doses were measured with two cylindrical ion chambers inserted into an anthropomorphic spine phantom. Our study indicated that the Monaco treatment planning system (TPS) could generate clinical treatment plans for the MRL that were of comparable quality to the RayStation TPS with a conventional Linac. For both Linacs the planned dose within the gross tumor volume agreed with measurements within ±3%. For the spinal cord, while the measured doses from the TrueBeam were 1.8% higher for the lumbar spine plan and 6.9% higher for thoracic spine plan, the measured doses from MRL were 0.6% lower for the lumbar spine plan and 3.9% higher for the thoracic spine plan. In conclusion, the feasibility of spine SBRT in Elekta Unity MRL has been demonstrated, however, more effort is needed for such as optimizing the online plan adaptation method.

Indexed as

Spine SBRTTrueBeamUnity MR-Linac

Identifiers

PMID33282466
PMCPMC7717094

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.