Evidence map›Paper›PMID 33282461›Full record

ArticleACS catalysis2020

Nature's Machinery, Repurposed: Expanding the Repertoire of Iron-Dependent Oxygenases.

Noah P Dunham, Frances H Arnold

Open access · greenAbstract read
In one paragraph

Article in ACS catalysis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 151 citations in OpenAlex.

  1. Article
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  5. Review
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  10. Enzymatic Stereodivergent Synthesis of Azaspiro[2.y]alkanes.Journal of the American Chemical Society · 2025
    Article
  11. Article
  12. Article
  13. Insights into Active Site Cysteine Residues inInternational journal of molecular sciences · 2025
    Review
  14. Stabilization of the Ferryl═Oxoheme Form ofJournal of the American Chemical Society · 2025
    Article
  15. Review
  16. Article
  17. Ni-catalysed remote C(spNature reviews. Chemistry · 2024
    Review
  18. Article
  19. Article
  20. Elucidating the Role of OACS environmental Au · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Noah P DunhamDivision of Chemistry and Chemical Engineering, California Institute of Technology, 1200 East California Boulevard, MC 210-41, Pasadena, California 91125, United States.ORCID 0000-0001-8006-9566
Frances H ArnoldDivision of Chemistry and Chemical Engineering, California Institute of Technology, 1200 East California Boulevard, MC 210-41, Pasadena, California 91125, United States.ORCID 0000-0002-4027-364X
California Institute of Technology · US

Funding

Prenylated-Flavin Enzymes as a new Platform for Drug Synthesis and DiscoveryF32GM131620 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI DUNHAM, NOAH PAUL · 2019 to 2020
$126k
NIGMS NIH HHS F32 GM131620
6 · The paper itself

Abstract

Iron is an especially important redox-active cofactor in biology because of its ability to mediate reactions with atmospheric O

Indexed as

biocatalysiscytochrome P450directed evolutionenzymologymechanismoxygenase

Identifiers

PMID33282461
PMCPMC7710332
OpenAlexW3089838238

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.