Evidence map›Paper›PMID 33282373›Full record

ArticleJournal of thoracic disease2020

Long-term prognosis in patients with end-stage renal disease after coronary artery bypass grafting.

Philip Y K Pang, Christopher K J Teow, Ming Jie Huang, Madhava J Naik, See Lim Lim, Victor T T Chao, Teing Ee Tan, Yeow Leng Chua, Yoong Kong Sin

Open access · diamondAbstract read
In one paragraph

Article in Journal of thoracic disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Philip Y K PangDepartment of Cardiothoracic Surgery, National Heart Centre Singapore, Singapore.
Christopher K J TeowMinistry of Health Holdings, Singapore.
Ming Jie HuangDepartment of Cardiothoracic Surgery, National Heart Centre Singapore, Singapore.
Madhava J NaikDepartment of Cardiothoracic Surgery, National Heart Centre Singapore, Singapore.
See Lim LimDepartment of Cardiothoracic Surgery, National Heart Centre Singapore, Singapore.
Victor T T ChaoDepartment of Cardiothoracic Surgery, National Heart Centre Singapore, Singapore.
Teing Ee TanDepartment of Cardiothoracic Surgery, National Heart Centre Singapore, Singapore.
Yeow Leng ChuaDepartment of Cardiothoracic Surgery, National Heart Centre Singapore, Singapore.
Yoong Kong SinDepartment of Cardiothoracic Surgery, National Heart Centre Singapore, Singapore.
National Heart Centre Singapore · SGMinistry of Health · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiovascular disease is a major cause of morbidity and mortality in patients with end-stage renal disease (ESRD). Coronary artery bypass grafting (CABG) is beneficial in selected patients with ESRD. This study investigates the survival outcomes and prognostic factors in ESRD patients who underwent CABG.

methodsA retrospective analysis was performed for 149 patients with ESRD who underwent isolated CABG between 2006 and 2015.

resultsMean age was 59.4±8.7 years and 106 patients (71.1%) were male. Operative mortality occurred in 20 patients (13.4%). Overall survival was 81.1%±3.2% at 1 year, 41.5%±4.3% at 5 years and 19.2%±4.2% at 10 years. Median survival was 4.3 years. Multivariable analysis identified age [P=0.001, odds ratio (OR): 1.15 per 1-year increase, 95% confidence interval (CI): 1.06-1.25], preoperative left ventricular ejection fraction (LVEF) (P=0.020, OR: 0.94, 95% CI: 0.89-0.99) and non-elective status of operation (P=0.049, OR: 3.34, 95% CI: 1.00-11.1) as predictors of operative mortality. Cox regression analysis identified age [P<0.001, hazard ratio (HR): 1.05 per 1-year increase, 95% CI: 1.03-1.08], New York Heart Association (NYHA) class III or IV status (P=0.010, HR: 1.75, 95% CI: 1.15-2.67) and the use of a left internal mammary artery (LIMA) to left anterior descending artery (LIMA-LAD) graft (P=0.029, HR: 0.42, 95% CI: 0.19-0.92) as factors influencing long-term survival.

conclusionsCABG is associated with high operative mortality and poor long-term survival in ESRD patients. Age and NYHA class influenced late survival. LIMA-LAD grafting conferred a long-term survival advantage.

Indexed as

coronary artery bypass grafting (CABG)coronary artery diseasedialysis-dependent renal failureEnd-stage renal disease (ESRD)

Identifiers

PMID33282373
PMCPMC7711392
OpenAlexW3103317849

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.