ArticlePulmonary circulation
Diagnostic utility of sub-maximum cardiopulmonary exercise testing in the ambulatory setting for heart failure with preserved ejection fraction.
Article in Pulmonary circulation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 20 citations in OpenAlex.
- Noninvasive Gas Exchange Determinants of Exercise Hemodynamics in Non-Severe Pulmonary Hypertension Associated With Interstitial Lung Disease.Pulmonary circulation · 2026Article
- Beyond PVR: dynamic physiologic assessment enhances prognostic evaluation in pulmonary hypertension associated with chronic obstructive pulmonary disease.BMJ open respiratory research · 2026Article
- 3D echo derived right ventricular principal surface strain in pulmonary arterial hypertension.American journal of physiology. Heart and circulatory physiology · 2026Article
- Real-time CMR combined with cardiopulmonary exercise testing enables integrated assessment of cardiac function during exercise.Frontiers in cardiovascular medicine · 2026Article
- Preoperative submaximal cardiopulmonary exercise testing and its association with early postoperative complications.BJA open · 2025Article
- Implementation of Brief Submaximal Cardiopulmonary Testing in a High-Volume Presurgical Evaluation Clinic: Feasibility Cohort Study.JMIR perioperative medicine · 2025Observational
- The metabolic and physiologic impairments underlying long COVID associated exercise intolerance.Pulmonary circulation · 2024Article
- Differential cardiopulmonary haemodynamic phenotypes in PASC-related exercise intolerance.ERJ open research · 2024Article
- Cognitive impairment in pulmonary arterial hypertension.Annals of clinical and translational neurology · 2023Article
- Response to "Noninvasive determinants of pulmonary hypertension (PH) in interstitial lung disease (ILD)" by Joseph et al.Pulmonary circulation · 2023Article
- Diagnostic value of expired gas analysis in heart failure with preserved ejection fraction.Scientific reports · 2023Article
- Noninvasive determinants of pulmonary hypertension in interstitial lung disease.Pulmonary circulation · 2023Article
- Clinical Relevance of Right Atrial Functional Response to Treatment in Pulmonary Arterial Hypertension.Frontiers in cardiovascular medicine · 2021Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Pulmonary hypertension is commonly associated with heart failure with preserved ejection fraction. In heart failure with preserved ejection fraction, the elevated left-sided filling pressures result in isolated post-capillary pulmonary hypertension or combined pre- and post-capillary pulmonary hypertension. Although right heart catheterization is the gold standard for diagnosis, it is an invasive test with associated risks. The ability of sub-maximum cardiopulmonary exercise test as an adjunct diagnostic tool in pulmonary hypertension-associated heart failure with preserved ejection fraction is not known. Forty-six patients with heart failure with preserved ejection fraction and pulmonary hypertension (27 patients with combined pre- and post-capillary pulmonary hypertension and 19 patients with isolated post-capillary pulmonary hypertension) underwent sub-maximum cardiopulmonary exercise test followed by right heart catheterization. The study also included 18 age- and gender-matched control subjects. Several sub-maximum gas exchange parameters were examined to determine the ability of sub-maximum cardiopulmonary exercise test to distinguish between isolated post-capillary pulmonary hypertension and combined pre- and post-capillary pulmonary hypertension. Conventional echocardiogram measures did not distinguish between isolated post-capillary pulmonary hypertension and combined pre- and post-capillary pulmonary hypertension. Compared to isolated post-capillary pulmonary hypertension, combined pre- and post-capillary pulmonary hypertension had greater ventilatory equivalent for carbon dioxide (VE/VCO
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