ArticleDisease markers2020
Serum Anion Gap Is Associated with All-Cause Mortality among Critically Ill Patients with Congestive Heart Failure.
Article in Disease markers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Prognostic value of anion gap for patients with heart failure: a systematic review and meta-analysis.BMC cardiovascular disorders · 2024Pooled it
- Contribution of albumin-corrected anion gap and associated biomarkers to the mortality of patients with congestive heart failure: a retrospective cohort study.BMC cardiovascular disorders · 2025Article
- Impact of anion gap on in-hospital mortality in trauma-induced coagulopathy patients: a MIMIC-IV study.European journal of medical research · 2025Article
- Association of albumin-corrected anion gap with mortality in ICU patients with heart failure and acute kidney injury: analysis of the MIMIC-IV database.European journal of medical research · 2025Article
- Association between serum anion gap and all-cause mortality in critically ill patients with Gastrointestinal bleeding: insights from MIMIC-IV database.Scientific reports · 2025Article
- The association between anion gap and prognosis in patients myocardial infarction with congestive heart failure: a retrospective analysis of the MIMIC-IV database.International journal of emergency medicine · 2025Article
- Explainable machine learning and online calculators to predict heart failure mortality in intensive care units.ESC heart failure · 2025Article
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- Association between Albumin-Corrected Anion Gap and Mortality in Patients with Cardiogenic Shock.Reviews in cardiovascular medicine · 2024Article
- Association between serum anion gap and risk of in-hospital mortality in patients with acute heart failure.Scientific reports · 2024Article
- The association between serum anion gap and acute kidney injury after coronary artery bypass grafting in patients with acute coronary syndrome.BMC cardiovascular disorders · 2023Article
- Serum anion gap is associated with mortality in intensive care unit patients with diastolic heart failure.Scientific reports · 2023Article
- Relationship Between Albumin-Corrected Anion Gap and Mortality in Hospitalized Heart Failure Patients.Cureus · 2023Article
- The association between serum anion gap and all-cause mortality of unselected adult patients: A retrospective cohort study of >20,000 patients.Journal of clinical laboratory analysis · 2023Article
- Applying an Improved Stacking Ensemble Model to Predict the Mortality of ICU Patients with Heart Failure.Journal of clinical medicine · 2022Article
- The Anion Gap and Mortality in Critically Ill Patients with Hip Fractures.Contrast media & molecular imaging · 2022Article
- Relationship of Admission Serum Anion Gap and Prognosis of Critically Ill Patients: A Large Multicenter Cohort Study.Disease markers · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCongestive heart failure (CHF) is a complex clinical syndrome, with high morbidity and mortality. Serum anion gap (SAG) is associated with the severity of various cardiovascular diseases. However, the role of SAG indicators in CHF is unclear. METHODS AND
resultsA retrospective analysis of data from Multiparameter Intelligent Monitoring in Intensive Care III version 1.4 was conducted in critically ill patients with CHF. The clinical information of each patient, including demographic data, comorbidities, vital signs, scores, and laboratory indicators, were successfully obtained. Cox proportional hazards models were used to determine the relationship between SAG and mortality in patients with CHF, the consistency of which was further verified by subgroup analysis.
resultsA total of 7426 subjects met the inclusion criteria. Multivariate analysis showed that after adjusting for age, gender, ethnicity, and other potential confounders, increased SAG was significantly related to an increase in 30- and 90-day all-cause mortalities of critically ill patients with CHF compared with decreased SAG (tertile 3 versus tertile 1: adjusted hazard ratio, 95% confidence interval: 1.74, 1.46-2.08; 1.53, 1.32-1.77). Subgroup analysis indicated that the association between SAG and all-cause mortality presented similarities in most strata.
conclusionSAG at admission could be a promising predictor of all-cause mortality in critically ill patients with CHF.
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