Evidence map›Paper›PMID 33281887›Full record

ArticleThe journal of venomous animals and toxins including tropical diseases2020

Chicken antibodies against venom proteins of

Chi-Hsin Lee, Chia-I Liu, Sy-Jye Leu, Yu-Ching Lee, Jen-Ron Chiang, Liao-Chun Chiang, Yan-Chiao Mao, Bor-Yu Tsai, Ching-Sheng Hung, Chi-Ching Chen and 1 more

Open access · goldAbstract read
In one paragraph

Article in The journal of venomous animals and toxins including tropical diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 3 countries.

Chi-Hsin LeeSchool of Medical Laboratory Science and Biotechnology, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.
Chia-I LiuSchool of Medical Laboratory Science and Biotechnology, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.
Sy-Jye LeuGraduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Yu-Ching LeeThe Center of Translational Medicine, Taipei Medical University, Taipei, Taiwan.
Jen-Ron ChiangCenter for Research, Diagnostics and Vaccine Development, Centers for Disease Control, Ministry of Health and Welfare, Taiwan.
Liao-Chun ChiangCollege of Life Sciences, National Tsing Hua University, Hsinchu, Taiwan.ORCID 0000-0003-4846-1837
Yan-Chiao MaoDivision of Clinical Toxicology, Department of Emergency Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.ORCID 0000-0002-8561-0582
Bor-Yu TsaiNavi Bio-Therapeutics Inc., Taipei, Taiwan.
Ching-Sheng HungDepartment of Laboratory Medicine, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.
Chi-Ching ChenDepartment of Pathology and Laboratory Medicine, Landseed Hospital, Taoyuan, Taiwan.
Yi-Yuan YangSchool of Medical Laboratory Science and Biotechnology, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.ORCID 0000-0003-2534-8436
Taipei Medical University · TWIo Therapeutics (United States) · USLandseed Hospital · TWMinistry of Health and Welfare · KRNational Tsing Hua University · TWTaichung Veterans General Hospital · TWWan Fang Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe venom of bamboo vipers (

methods

resultsPurified IgY from egg yolk showed the specific binding ability to TS proteins. The dimensions of these two libraries contain 2.4 × 10

conclusionChickens were excellent hosts for the production of neutralization antibodies at low cost. Phage display technology is available for generation of monoclonal antibodies against snake venom proteins. These antibodies could be applied in the development of diagnostic kits or as an alternative for snakebite envenomation treatment in the near future.

Indexed as

IgY antibodyPhage display technologySingle-chain variable fragment antibodyTrimeresurus stejnegeri

Identifiers

PMID33281887
PMCPMC7682652
OpenAlexW3110323878

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.