ReviewFrontiers in neuroscience2020
The Role of Heart Rate Variability in the Future of Remote Digital Biomarkers.
Review in Frontiers in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Impact of SARS-CoV-2 Infection on Heart Rate Variability: A Systematic Review of Observational Studies with Control Groups.International journal of environmental research and public health · 2023Pooled it
- Smartphone as a Disease Screening Tool: A Systematic Review.Sensors (Basel, Switzerland) · 2022Pooled it
- Resting State Heart Rate Variability in Depression: An Introductory Narrative Review of Cross-Sectional and Longitudinal Evidence.Journal of personalized medicine · 2026Review
- Artificial intelligence in neurocardiology: decoding brain-heart network interactions for clinical and translational insights.Frontiers in neuroscience · 2026Review
- Lived experiences and perspectives of persons with conditions marked by autonomic dysfunction.PloS one · 2026Article
- Heart Rate Variability Applications in Medical Specialties: A Narrative Review.Applied psychophysiology and biofeedback · 2025Review
- Synchronous post-exercise electrocardiogram, phonocardiogram, photoplethysmograms and seismocardiogram.Scientific data · 2025Article
- Classification of Individuals With COVID-19 and Post-COVID-19 Condition and Healthy Controls Using Heart Rate Variability: Machine Learning Study With a Near-Real-Time Monitoring Component.Journal of medical Internet research · 2025Article
- Reactivity of the Autonomic Nervous System During Visual-Physical Incongruent Walking Conditions-A Virtual Reality Study.Psychophysiology · 2025Article
- The Impact of Stress on Autoimmune Disorders: Type 1 Diabetes Mellitus and Systemic Lupus Erythematosus.Cureus · 2025Review
- Neuro-Nutrition and Exercise Synergy: Exploring the Bioengineering of Cognitive Enhancement and Mental Health Optimization.Bioengineering (Basel, Switzerland) · 2025Review
- Predicting lymphovascular space invasion in early-stage cervical squamous cell carcinoma using heart rate variability.Frontiers in oncology · 2025Article
- Remote fitness assessment in younger and middle-aged to older adults: a comparison between laboratory- and videoconference-based assessment of selected measures of physical and cognitive fitness.BMC sports science, medicine & rehabilitation · 2024Article
- Shifting From Active to Passive Monitoring of Alzheimer Disease: The State of the Research.Journal of the American Heart Association · 2024Review
- Autonomic nervous system flexibility for understanding brain aging.Ageing research reviews · 2023Review
- A scoping review of neurodegenerative manifestations in explainable digital phenotyping.NPJ Parkinson's disease · 2023Article
- Autonomic response to walk tests is useful for assessing outcome measures in people with multiple sclerosis.Frontiers in physiology · 2023Article
- Digital biomarkers and sex impacts in Alzheimer's disease management - potential utility for innovative 3P medicine approach.The EPMA journal · 2022Article
- The Movesense Medical Sensor Chest Belt Device as Single Channel ECG for RR Interval Detection and HRV Analysis during Resting State and Incremental Exercise: A Cross-Sectional Validation Study.Sensors (Basel, Switzerland) · 2022Article
- Trends in Daily Heart Rate Variability Fluctuations Are Associated with Longitudinal Changes in Stress and Somatisation in Police Officers.Healthcare (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heart rate variability (HRV) offers insights into humoral, neural and neurovisceral processes in health and disorders of brain, body and behavior but has yet to be fully potentiated in the digital age. Remote measurement technologies (RMTs), such as, smartphones, wearable sensors or home-based devices, can passively capture HRV as a nested parameter of neurovisceral integration and health during everyday life, providing insights across different contexts, such as activities of daily living, therapeutic interventions and behavioral tasks, to compliment ongoing clinical care. Many RMTs measure HRV, even consumer wearables and smartphones, which can be deployed as wearable sensors or digital cameras using photoplethysmography. RMTs that measure HRV provide the opportunity to identify digital biomarkers indicative of changes in health or disease status in disorders where neurovisceral processes are compromised. RMT-based HRV therefore has potential as an adjunct digital biomarker in neurovisceral digital phenotyping that can add continuously updated, objective and relevant data to existing clinical methodologies, aiding the evolution of current "diagnose and treat" care models to a more proactive and holistic approach that pairs established markers with advances in remote digital technology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.