Evidence map›Paper›PMID 33281368›Full record

ArticleVeterinary world2020

The combined effect of magnetic and electric fields using on/off infrared light on the blood sugar level and the diameter of Langerhans islets of diabetic mice.

S Suhariningsih, Suryani Dyah Astuti, Saikhu Akhmad Husen, Dwi Winarni, Dian Astri Rahmawati, Akhmad Taufiq Mukti, Alfian Pramudita Putra, Muhammad Miftahussurur

Abstract read
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Article in Veterinary world, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

S SuhariningsihDepartment of Physics, Faculty of Sciences and Technology, Universitas Airlangga, Surabaya 60115, Indonesia.
Suryani Dyah AstutiDepartment of Physics, Faculty of Sciences and Technology, Universitas Airlangga, Surabaya 60115, Indonesia.
Saikhu Akhmad HusenDepartment of Biology, Faculty of Science and Technology, Universitas Airlangga, Surabaya, 60115, Indonesia.
Dwi WinarniDepartment of Biology, Faculty of Science and Technology, Universitas Airlangga, Surabaya, 60115, Indonesia.
Dian Astri RahmawatiDepartment of Biology, Faculty of Science and Technology, Universitas Airlangga, Surabaya, 60115, Indonesia.
Akhmad Taufiq MuktiDepartment of Fish Health Management and Aquaculture, Faculty of Fisheries and Marine, Universitas Airlangga, Surabaya 60115, Indonesia.
Alfian Pramudita PutraBiomedical Engineering Study Program, Department of Physics, Faculty of Sciences and Technology, Universitas Airlangga, Surabaya 60115, Indonesia.
Muhammad MiftahussururDepartment of Internal Medicine, Division of Gastroentero-Hepatology, Faculty of Medicine, Institute of Tropical Diseases, Universitas Airlangga, Surabaya, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimAt present, diabetes is treated with oral antidiabetic medicines, such as sulfonylureas and thiazolidine, as well as insulin injection. However, these methods have several shortcomings. Therefore, alternatives for treating diabetes mellitus (DM) are needed. This study aims to determine the combined effect of magnetic and electric fields on blood sugar levels and the diameter of Langerhans islets of diabetic mice. MATERIALS AND

methodsInduction of DM in mice was carried out by administering lard for 2 weeks and continued with an intraperitoneal injection of streptozotocin, dissolved in a 4.5 pH citrate buffer, and administered in a dose of 30 mg/kg bodyweight for 5 days. Treatments were used in combination with magnetic and electric fields using on/off infrared light. Blood samples were pipetted through the tip of mice's tails to establish the blood sugar level for each individual mouse. Histology preparation of the pancreas organ was affected using the histology standard as well as hematoxylin and eosin staining methods. Langerhans islet diameter data were analyzed using analysis of variance followed by Duncan's multiple range test. Data analysis was performed at ssssssss=0.05.

resultsThe results showed that the combined treatment of permanent magnetic and unidirectional electric fields (PS) caused changes in blood sugar levels that were not significantly different from the normal control group. The PS treatment improved the diameter of the Langerhans islets but not to a significant degree compared to other treatments.

conclusionThe use of PS treatment is effective for reducing the blood sugar levels of diabetic mice and improving the diameter of their Langerhans islets.

Indexed as

blood sugar leveldiabetic miceelectric fieldinfrared lightLangerhans islets diametermagnetic field

Identifiers

PMID33281368
PMCPMC7704297

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.