Evidence map›Paper›PMID 33281353›Full record

ArticleVeterinary world2020

Antileishmanial and cytotoxic activities of four Andean plant extracts from Colombia.

Wilson Cardona-G, Sara Robledo, Fernando Alzate, Andrés F Yepes, Cristian Hernandez, Ivan Dario Velez, Juan Carlos Calderon, Isabel Vásquez Tabares

Abstract read
In one paragraph

Article in Veterinary world, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wilson Cardona-GChemistry of Colombian Plants, Institute of Chemistry, Natural and Exact Sciences Faculty, Universidad de Antioquia, Colombia.
Sara RobledoGroup of Botanical Studies, Institute of Biology, Natural and Exact Sciences Faculty, Universidad de Antioquia, Colombia.
Fernando AlzatePECET, Medical Research Institute, School of Medicine, Universidad de Antioquia, Colombia.
Andrés F YepesChemistry of Colombian Plants, Institute of Chemistry, Natural and Exact Sciences Faculty, Universidad de Antioquia, Colombia.
Cristian HernandezChemistry of Colombian Plants, Institute of Chemistry, Natural and Exact Sciences Faculty, Universidad de Antioquia, Colombia.
Ivan Dario VelezGroup of Botanical Studies, Institute of Biology, Natural and Exact Sciences Faculty, Universidad de Antioquia, Colombia.
Juan Carlos CalderonChemistry of Colombian Plants, Institute of Chemistry, Natural and Exact Sciences Faculty, Universidad de Antioquia, Colombia.
Isabel Vásquez TabaresChemistry of Colombian Plants, Institute of Chemistry, Natural and Exact Sciences Faculty, Universidad de Antioquia, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimMATERIALS AND

methodsExtracts were obtained by percolation with solvents of different polarities - hexane, dichloromethane, ethyl acetate, and ethanol. Phytochemical screening was conducted based on reported methods. All products were evaluated

resultsFlavonoids, triterpenes, and tannins were the main secondary metabolites found. From the results, dichloromethane extracts from O.F and P.B, ethanol extract from P.B, and ethyl acetate extracts of all plants were active, with EC

conclusionBased on the activity we observed, ethyl acetate extract can continue in its usage in the search for new antileishmanial drugs, mainly ethyl acetate extract from L.S showed activity comparable to meglumine antimoniate and was not cytotoxic.

Indexed as

AraliaceaeChrysobalanaceaeLauraceaeLeishmaniasisLicania salicifoliaOreopanax floribundusPersea ferrugineaPsychotria buchtieniiRubiaceae

Identifiers

PMID33281353
PMCPMC7704314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.