Evidence map›Paper›PMID 33281342›Full record

ArticleVeterinary world2020

The distribution pattern and growth factor level in platelet-rich fibrin incorporated skin-derived mesenchymal stem cells: An

Igo Syaiful Ihsan, Deya Karsari, Nora Ertanti, Aristika Dinaryanti, Alexander Patera Nugraha, Purwati Purwati, Sri Agus Sudjarwo, Fedik Abdul Rantam

Open access · goldAbstract read
In one paragraph

Article in Veterinary world, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Igo Syaiful IhsanMaster Student of Vaccinology and Immunotherapeutica, Veterinary Medicine Faculty, Airlangga University, Surabaya, Indonesia.
Deya KarsariStem Cell Research and Development Center, Airlangga University, Surabaya, Indonesia.
Nora ErtantiStem Cell Research and Development Center, Airlangga University, Surabaya, Indonesia.
Aristika DinaryantiStem Cell Research and Development Center, Airlangga University, Surabaya, Indonesia.
Alexander Patera NugrahaDoctoral Student of Medical Science, Faculty of Medicine, Airlangga University, Surabaya, Indonesia.
Purwati PurwatiStem Cell Research and Development Center, Airlangga University, Surabaya, Indonesia.
Sri Agus SudjarwoDepartment of Pharmacology, Veterinary Medicine Faculty, Airlangga University, Surabaya, Indonesia.
Fedik Abdul RantamStem Cell Research and Development Center, Airlangga University, Surabaya, Indonesia.
Airlangga University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimA skin wound in an animal must be cared for to prevent further health issues. Platelet-rich fibrin (PRF) and skin-derived mesenchymal stem cells (SMSCs) have been reported to have potential in increasing the rate of wound healing. This study aimed to analyze the distribution patterns and levels of platelet-derived growth factor (PDGF), insulin-like growth factor (IGF), vascular endothelial growth factor (VEGF), and transforming growth factor-β (TGF-β) in PRF incorporated with SMSCs. MATERIALS AND

methodsThis study employed a true experiment (

resultsGroup D had the most morphologically visible SMSCs attached to the PRF, with elongated and pseudopodia cells. There was a significant difference between the levels of growth factor in Groups A and D (p=0.0001; p<0.01).

conclusionSMSCs were able to adhere to and distribute evenly on the surface of PRF after 5 days of incubation. The PRF incorporated SMSCs contained high levels of PDGF, IGF, VEGF, and TGF- β, which may prove to have potential in enhancing wound healing.

Indexed as

growth factorplatelet-rich fibrinrabbitskin mesenchymal stem cells

Identifiers

PMID33281342
PMCPMC7704299
OpenAlexW3092014488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.