Evidence map›Paper›PMID 33281160›Full record

ArticleInternal medicine (Tokyo, Japan)2021

The Usefulness of a Transbronchial Lung Cryobiopsy for Diffuse Bronchiolitis.

Hideaki Yamakawa, Tamiko Takemura, Shintaro Sato, Tomohiko Nakamura, Tomotaka Nishizawa, Tomohiro Oba, Rie Kawabe, Keiichi Akasaka, Masako Amano, Kazuyoshi Kuwano and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Bronchiolar disorders in systemic autoimmune rheumatic diseases.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Hideaki YamakawaDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Japan.
Tamiko TakemuraDepartment of Pathology, Kanagawa Cardiovascular and Respiratory Center, Japan.
Shintaro SatoDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Japan.
Tomohiko NakamuraDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Japan.
Tomotaka NishizawaDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Japan.
Tomohiro ObaDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Japan.
Rie KawabeDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Japan.
Keiichi AkasakaDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Japan.
Masako AmanoDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Japan.
Kazuyoshi KuwanoDepartment of Respiratory Medicine, Tokyo Jikei University Hospital, Japan.
Hidekazu MatsushimaDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Japan.
Saitama Red Cross Hospital · JPKanagawa Cardiovascular and Respiratory Center · JPThe Jikei University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report four cases of diffuse bronchiolitis proven by a transbronchial lung cryobiopsy (TBLC). Based on various aspects, including the pathological findings, we definitively diagnosed two patients with diffuse panbronchiolitis (DPB) and the other two with primary ciliary dyskinesia (PCD). One of the DPB patients had more severe peribronchiolar fibrosis than the other, and the disease course was refractory to macrolide therapy. One of the PCD patients was additionally diagnosed with combined constrictive bronchiolitis. This report highlights the importance of a TBLC in the differentiation of bronchiolitis, suggesting its utility for helping pulmonologists formulate a treatment strategy.

Indexed as

BronchiolitisBronchiolitis ObliteransCiliary Motility DisordersHaemophilus InfectionsHumansLungconstrictive bronchiolitisdiffuse panbronchiolitisprimary ciliary dyskinesiatransbronchial lung cryobiopsy

Identifiers

PMID33281160
PMCPMC8170248
OpenAlexW3111354281

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.