Evidence map›Paper›PMID 33281111›Full record

ArticleHematology, transfusion and cell therapy

Minimal residual disease assessment in acute lymphoblastic leukemia by 4-color flow cytometry: Recommendations from the MRD Working Group of the Brazilian Society of Bone Marrow Transplantation.

Maura R V Ikoma-Colturato, Miriam P Beltrame, Felipe M Furtado, Glicinia Pimenta, Elaine Sobral da Costa, Ana Paula Azambuja, Mariester Malvezzi, Mihoko Yamamoto, SBTMO MRD working group

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Article in Hematology, transfusion and cell therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maura R V Ikoma-ColturatoHospital Amaral Carvalho, Jaú, SP, Brazil; Sabin Medicina Diagnóstica, Brasília, DF, Brazil. Electronic address: maura.ikoma@amaralcarvalho.org.br.
Miriam P BeltrameHospital Erasto Gaertner, Curitiba, PR, Brazil.
Felipe M FurtadoSabin Medicina Diagnóstica, Brasília, DF, Brazil; Hospital da Criança de Brasília José de Alencar, Brasilia, DF, Brazil, Brazil.
Glicinia PimentaUniversidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil.
Elaine Sobral da CostaUniversidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil.
Ana Paula AzambujaHospital de Clínicas Universidade Federal do Paraná (UFPR), Curitiba, PR, Brazil.
Mariester MalvezziHospital de Clínicas Universidade Federal do Paraná (UFPR), Curitiba, PR, Brazil.
Mihoko YamamotoUniversidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.
SBTMO MRD working group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe minimal residual disease (MRD) status plays a crucial role in the treatment of acute lymphoblastic leukemia (ALL) and is currently used in most therapeutic protocols to guide the appropriate therapeutic decision. Therefore, it is imperative that laboratories offer accurate and reliable results through well standardized technical processes by establishing rigorous operating procedures.

methodOur goal is to propose a monoclonal antibody (MoAb) panel for MRD detection in ALL and provide recommendations intended for flow cytometry laboratories that work on 4-color flow cytometry platforms. RESULTS AND

conclusionThe document includes pre-analytical and analytical procedures, quality control assurance, technical procedures, as well as the information that needs to be included in the reports for clinicians.

Indexed as

Acute lymphoblastic leukemiaFlow cytometryMinimal residual disease

Identifiers

PMID33281111
PMCPMC8446261

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.