ArticleBMC medicine2020
Sleep disturbances and the speed of multimorbidity development in old age: results from a longitudinal population-based study.
Article in BMC medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
48 citing papers in PubMed, 2 syntheses or guidelines pooled it, 78 citations in OpenAlex.
- Prevalence of sleep disturbance in patients with ankylosing spondylitis: a systematic review and meta-analysis.Advances in rheumatology (London, England) · 2023Pooled it
- Sleep Problems Associate With Multimorbidity: A Systematic Review and Meta-analysis.Public health reviews · 2023Pooled it
- Long-term health conditions and their impact on people with sleep disturbances and dementia.BMC geriatrics · 2025Trial
- Habitual fasting duration and accelerated multimorbidity in older adults.Journal of internal medicine · 2026Article
- Multimorbidity and Cognitive Function in Community-Dwelling Older Adults in Shanghai: The Mediating Role of Sleep Quality.Journal of sleep research · 2026Article
- Differential item functioning of PROMIS Sleep Disturbance-Short Form 8a across levels of health literacy in a community sample of adults.Psychological assessment · 2026Article
- Article
- Sleep disturbances and their relationship with anxiety-depressive symptoms and quality of life in older adults: a retrospective observational study.Open medicine (Warsaw, Poland) · 2026Article
- Association between sleep, sunlight exposure, and multimorbidity in older adults with and without mental illness.Frontiers in public health · 2026Article
- Association Between the Jiangnan Diet and Mild Cognitive Impairment Among the Elderly.Nutrients · 2025Article
- Exposure to light and noise at night, and sleep quality in community-dwelling older adults: a cross-sectional study.European geriatric medicine · 2025Article
- Examining sleep health and its associations with technology use among older adults in Sweden: insights from a population-based study.BMC public health · 2025Article
- Association between sleep disorders and osteoporosis in the elderly at high altitude in China.Sleep and biological rhythms · 2025Article
- Long sleep duration, cognitive performance, and the moderating role of depression: A cross-sectional analysis in the Framingham Heart Study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Associations between multimorbidity burden and objective and patient-reported sleep outcomes among people with HIV.AIDS (London, England) · 2025Article
- Association Between Chronic Pain, Coping Strategies, and Sleep Quality in Rural Chinese Older Adults: A Cross-Sectional Study.Clinical interventions in aging · 2025Observational
- Sleep Disturbance in People with Anxiety or Depressive Disorders over 30 Years, and the Influence of Personality Disorder.Behavioral sleep medicine · 2024Article
- Resilience among older adults with multimorbidity using the Connor-Davidson scale in the Canadian Longitudinal Study on Aging: health behaviour, socio-economic, and social support predictors.BMC public health · 2024Article
- Characteristics of Atypical Sleep Durations Among Older Compared to Younger Adults: Evidence from the New Zealand Health Survey.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Eating disorders and physical multimorbidity in the English general population.Eating and weight disorders : EWD · 2023Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSleep disturbances are prevalent among older adults and are associated with various individual diseases. The aim of this study was to investigate whether sleep disturbances are associated with the speed of multimorbidity development among older adults.
methodsData were gathered from the Swedish National study of Aging and Care in Kungsholmen (SNAC-K), an ongoing population-based study of subjects aged 60+ (N = 3363). The study included a subsample (n = 1189) without multimorbidity at baseline (< 2 chronic diseases). Baseline sleep disturbances were derived from the Comprehensive Psychiatric Rating Scale and categorized as none, mild, and moderate-severe. The number of chronic conditions throughout the 9-year follow-up was obtained from clinical examinations. Linear mixed models were used to study the association between sleep disturbances and the speed of chronic disease accumulation, adjusting for sex, age, education, physical activity, smoking, alcohol consumption, depression, pain, and psychotropic drug use. We repeated the analyses including only cardiovascular, neuropsychiatric, or musculoskeletal diseases as the outcome.
resultsModerate-severe sleep disturbances were associated with a higher speed of chronic disease accumulation (ß/year = 0.142, p = 0.008), regardless of potential confounders. Significant positive associations were also found between moderate-severe sleep disturbances and neuropsychiatric (ß/year = 0.041, p = 0.016) and musculoskeletal (ß/year = 0.038, p = 0.025) disease accumulation, but not with cardiovascular diseases. Results remained stable when participants with baseline dementia, cognitive impairment, or depression were excluded.
conclusionThe finding that sleep disturbances are associated with faster chronic disease accumulation points towards the importance of early detection and treatment of sleep disturbances as a possible strategy to reduce chronic multimorbidity among older adults.
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