Evidence map›Paper›PMID 33280487›Full record

ArticleTissue engineering. Part C, Methods2021

A Novel Three-Dimensional Skin Disease Model to Assess Macrophage Function in Diabetes.

Avi Smith, Trishawna Watkins, Georgios Theocharidis, Irene Lang, Maya Leschinsky, Anna Maione, Olga Kashpur, Theresa Raimondo, Sahar Rahmani, Jeremy Baskin and 3 more

Open access · greenAbstract read
In one paragraph

Article in Tissue engineering. Part C, Methods, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Immunomodulatory Tissue-Engineering Strategies for Diabetic Foot Ulcer Management: A Systematic Review.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Pooled it
  4. Review
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  8. Article
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  14. PreclinicalFrontiers in bioengineering and biotechnology · 2023
    Review
  15. Article
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  17. Article
  18. An Autologous, Vascularized and Immunocompetent Tissue Engineered Skin to Highlight Inter-Individual Variability to Better Understand the Human Wound Healing.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Avi SmithDepartment of Diagnostic Science, Tufts University School of Dental Medicine, Boston, Massachusetts, USA.
Trishawna WatkinsDepartment of Diagnostic Science, Tufts University School of Dental Medicine, Boston, Massachusetts, USA.
Georgios TheocharidisMicrocirculation Laboratory and Joslin-Beth Israel Deaconess Foot Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Irene LangDepartment of Diagnostic Science, Tufts University School of Dental Medicine, Boston, Massachusetts, USA.
Maya LeschinskyDepartment of Diagnostic Science, Tufts University School of Dental Medicine, Boston, Massachusetts, USA.
Anna MaioneDepartment of Diagnostic Science, Tufts University School of Dental Medicine, Boston, Massachusetts, USA.
Olga KashpurDepartment of Diagnostic Science, Tufts University School of Dental Medicine, Boston, Massachusetts, USA.
Theresa RaimondoWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, Massachusetts, USA.
Sahar RahmaniWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, Massachusetts, USA.
Jeremy BaskinDepartment of Diagnostic Science, Tufts University School of Dental Medicine, Boston, Massachusetts, USA.
David MooneyWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, Massachusetts, USA.
Aristidis VevesMicrocirculation Laboratory and Joslin-Beth Israel Deaconess Foot Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Jonathan GarlickDepartment of Diagnostic Science, Tufts University School of Dental Medicine, Boston, Massachusetts, USA.
Tufts University · USBeth Israel Deaconess Medical Center · USHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A major challenge in the management of patients suffering from diabetes is the risk of developing nonhealing foot ulcers. Most

Indexed as

Diabetes MellitusDiabetic FootFibroblastsHumansMacrophagesSkinWound Healingdiabetesdiabetic foot ulcerhuman skin equivalentmacrophageskin model

Identifiers

PMID33280487
PMCPMC8349718
OpenAlexW3113237787

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.