Evidence map›Paper›PMID 33280274›Full record

ReviewPharmacology research & perspectives2020

Psychedelic-assisted therapy for functional neurological disorders: A theoretical framework and review of prior reports.

Benjamin Stewart, Jon G Dean, Adriana Koek, Jason Chua, Rafael Wabl, Kayla Martin, Naveed Davoodian, Christopher Becker, Mai Himedan, Amanda Kim and 3 more

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in Pharmacology research & perspectives, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Psychedelics, epilepsy, and seizures: a review.Frontiers in pharmacology · 2023
    Review
  5. Review
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Benjamin StewartDepartment of Neurology, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-4376-5244
Jon G DeanDepartment of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.
Adriana KoekDepartment of Neurology, University of Michigan, Ann Arbor, MI, USA.
Jason ChuaDepartment of Neurology, University of Michigan, Ann Arbor, MI, USA.
Rafael WablDepartment of Neurology, University of Michigan, Ann Arbor, MI, USA.
Kayla MartinDepartment of Neurology, University of Michigan, Ann Arbor, MI, USA.
Naveed DavoodianNational Herbarium of Victoria, Melbourne, VIC, Australia.
Christopher BeckerDepartment of Neurology, University of Michigan, Ann Arbor, MI, USA.
Mai HimedanDepartment of Neurology, University of Michigan, Ann Arbor, MI, USA.
Amanda KimUniversity of Chicago Pritzker School of Medicine, Chicago, IL, USA.
Roger AlbinDepartment of Neurology, University of Michigan, Ann Arbor, MI, USA.
Kelvin L ChouDepartment of Neurology, University of Michigan, Ann Arbor, MI, USA.
Vikas KotagalDepartment of Neurology, University of Michigan, Ann Arbor, MI, USA.
University of Michigan · USAustralian National Herbarium · AUUniversity of Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Functional neurological disorders (FNDs), which are sometimes also referred to as psychogenic neurological disorders or conversion disorder, are common disabling neuropsychiatric disorders with limited treatment options. FNDs can present with sensory and/or motor symptoms, and, though they may mimic other neurological conditions, they are thought to occur via mechanisms other than those related to identifiable structural neuropathology and, in many cases, appear to be triggered and sustained by recognizable psychological factors. There is intriguing preliminary evidence to support the use of psychedelic-assisted therapy in a growing number of psychiatric illnesses, including FNDs. We review the theoretical arguments for and against exploring psychedelic-assisted therapy as a treatment for FNDs. We also provide an in-depth discussion of prior published cases detailing the use of psychedelics for psychosomatic conditions, analyzing therapeutic outcomes from a contemporary neuroscientific vantage as informed by several recent neuroimaging studies on psychedelics and FNDs.

Indexed as

AdultAnimalsBayes TheoremBrainChildDystoniaFemaleHallucinogensHumansMaleMental DisordersNervous System DiseasesHallucinogens5-HT2Aconversion disorderhallucinogenshysteriapsychosomatic medicinereceptorserotonin

Identifiers

PMID33280274
PMCPMC7719191
OpenAlexW3110773874

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.