Evidence map›Paper›PMID 33280235›Full record

ArticleInfluenza and other respiratory viruses2021

Enterovirus D68 infection among hospitalized children with severe acute respiratory illness in El Salvador and Panama, 2012-2013.

Holly M Biggs, W Allan Nix, Jing Zhang, Shannon Rogers, Wilfrido Clara, Jorge H Jara, Rosalba Gonzalez, Kathia Luciani, Yarisa Sujey Brizuela, Dora Estripeaut and 11 more

Open access · goldAbstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 5 institutions in 5 countries.

Holly M BiggsNational Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.ORCID 0000-0002-4949-2232
W Allan NixNational Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Jing ZhangNational Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Shannon RogersNational Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Wilfrido ClaraNational Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.ORCID 0000-0003-3779-3449
Jorge H JaraCentro de Estudios en Salud, Universidad del Valle de Guatemala, Guatemala City, Guatemala.
Rosalba GonzalezGorgas Memorial Institute for Health Studies, Panama City, Panama.
Kathia LucianiHospital De Especialidades Pediátricas Omar Torrijos, Panama City, Panama.
Yarisa Sujey BrizuelaHospital San Juan De Dios, San Miguel, El Salvador.
Dora EstripeautHospital Del Niño, Panama City, Panama.
Juan Miguel CastilloHospital San Juan De Dios, Santa Ana, El Salvador.
Tirza De LeonHospital Materno Infantil José Domingo De Obaldía, David, Panama.
Mary CorroHospital De Especialidades Pediátricas Omar Torrijos, Panama City, Panama.
Ofelina VergaraHospital Del Niño, Panama City, Panama.
Rafael RaudaHospital San Juan De Dios, Santa Ana, El Salvador.
Evens G ChongHospital Materno Infantil José Domingo De Obaldía, David, Panama.
John T WatsonNational Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Eduardo Azziz-BaumgartnerNational Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Susan I GerberNational Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Suxiang TongNational Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Fatimah S DawoodNational Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Centers for Disease Control and Prevention · USHospital San Juan de Dios · VEHospital del Niño · PAInstituto Conmemorativo Gorgas de Estudios de la Salud · PAUniversidad del Valle de Guatemala · GT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We assessed EV-D68 epidemiology and phylogenetics among children aged ≤9 years hospitalized with severe acute respiratory illnesses at five sites in Panama and El Salvador during 2012-2013. Respiratory specimens positive for enterovirus or rhinovirus were tested by real-time RT-PCR for EV-D68, and partial VP1 gene sequences were determined. Of 715 enrolled children, 17 from sites in both countries were EV-D68-positive and commonly had a history of asthma or wheezing. Phylogenetically, 15 of 16 sequences fell into Clade B1, and one into Clade A2. The Central American EV-D68s were closely related genetically to contemporaneous strains from North America, South America, and the Caribbean.

Indexed as

Enterovirus D, HumanEnterovirus InfectionsRespiratory Tract InfectionsChildChild, HospitalizedDisease OutbreaksEl SalvadorHumansInfantPanamaacute respiratory illnessCentral AmericaEl SalvadorEnterovirus D68Panamarespiratory virus

Identifiers

PMID33280235
PMCPMC7902261
OpenAlexW3113053893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.