Evidence map›Paper›PMID 33280213›Full record

ArticleInternational journal of clinical practice2021

Is mean platelet volume a predictive marker for the diagnosis of COVID-19 in children?

Huseyin Gumus, Abit Demir, Ahmet Yükkaldıran

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Huseyin GumusDepartment of Pediatrics, Harran University Faculty of Medicine, Sanliurfa, Turkey.ORCID https://orcid.org/0000-0002-9326-2194
Abit DemirDepartment of Pediatrics, Harran University Faculty of Medicine, Sanliurfa, Turkey.
Ahmet YükkaldıranOtolaryngology Department, Sanliurfa Education and Training Hospital, Sanliurfa, Turkey.ORCID https://orcid.org/0000-0002-1335-4110
Harran University · TRŞanlıurfa Mehmet Akif İnan Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the mean platelet volume (MPV) in asymptomatic children infected with COVID-19.

methodsThe study included 55 children infected with COVID-19 and 60 healthy children for the comparison of leukocyte and thrombocyte count, MPV and serum C-reactive protein (CRP) levels. Demographic data and clinical findings of all the participants were recorded, including age, gender, weight, temperature, cough, shortness of breath and contact history.

resultsThe MPV values were determined to be statistically significantly high (P < .001) and the lymphocyte values were significantly low (p:0.002) in the asymptomatic children infected with COVID-19 compared with the healthy control children. No difference was determined between the groups in respect of CRP level, leukocyte and thrombocyte counts (P > .05). The optimal cutoff point for MPV was determined as 8.74 fl (Area under the curve-AUC:0.932) with 81.82% sensitivity and 95% specificity for the determination of children infected with COVID-19. A cutoff value of <2.12/mm

conclusionThe results of this study indicate that MPV levels are significantly high in asymptomatic children infected with COVID-19 demonstrate that this is an important predictive value and has better predictive capacity than lymphocyte values. The evaluation of MPV and lymphocyte levels together could increase diagnostic success in asymptomatic COVID-19 patients.

Indexed as

COVID-19Mean Platelet VolumeBiomarkersCase-Control StudiesChildFemaleHumansMalePlatelet CountROC CurveSARS-CoV-2Biomarkers

Identifiers

PMID33280213
PMCPMC7883036
OpenAlexW3113171716

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.