ArticleJournal of perinatology : official journal of the California Perinatal Association2021
Prolonged transitional neonatal hypoglycaemia: characterisation of a clinical syndrome.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- International Guidelines for the Diagnosis and Management of Hyperinsulinism.Hormone research in paediatrics · 2024Guideline
- Diazoxide for Severe or Recurrent Neonatal Hypoglycemia: A Randomized Clinical Trial.JAMA network open · 2024Trial
- Trial
- Prevalence and safety of diazoxide in the neonatal intensive care unit.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Clinical and Hormonal Characteristics and Short-Term Outcomes of Diazoxide Use in Hypoglycemic Neonates: A Retrospective Cohort Study.Children (Basel, Switzerland) · 2026Article
- Characterization of congenital hyperinsulinism in Argentina: Clinical features, genetic findings, and treatment outcomes.PloS one · 2025Article
- Developing a congenital hyperinsulinism prioritized research agenda: a patient-driven international collaborative research network.Frontiers in endocrinology · 2025Article
- Neonatal Hypoglycemia and Neurocognitive Function at School Age: A Prospective Cohort Study.The Journal of pediatrics · 2024Article
- Neonatal hypoglycaemia.BMJ medicine · 2024Review
- Development and clinical application of a stability-indicating chromatography technique for the quantification of diazoxide.Heliyon · 2023Article
- What's in a name? That which we call perinatal stress hyperinsulinism by any other name would smell so bitter.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- Strategies to improve neurodevelopmental outcomes in babies at risk of neonatal hypoglycaemia.The Lancet. Child & adolescent health · 2021Review
- A better taxonomy for neonatal hypoglycemia is needed.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe performed a case-control study to characterise infants with "prolonged transitional hypoglycaemia".
methodsCases were born ≥36 weeks' gestation; had ≥1 hypoglycaemic episode <72 h and ≥72 h; received ongoing treatment for hypoglycaemia ≥72 h; and were without congenital disorders or acute illness. Cases were compared to controls born ≥36 weeks' with brief transitional hypoglycaemia, resolving <72 h.
results39/471 infants screened met case definition: 71.8% were male, 61.5% were small-for-gestational-age (SGA), and most were admitted <6 h. Compared to controls (N = 75), key risk factors for prolonged transitional hypoglycaemia were SGA (OR = 6.4, 95%CI 2.7-15.1), severe/recurrent hypoglycaemia <24 h (OR = 16.7, 95%CI 4.5-16.1), intravenous glucose bolus <24 h (OR = 26.6, 95%CI 9.4-75.1) and maximum glucose delivery rate <48 h of ≥8 mg/kg/min (OR = 25.5, 95%CI 7.7-84.1).
conclusionsInfants with prolonged transitional hypoglycaemia are predominantly male, SGA and have early severe/recurrent hypoglycaemia requiring glucose boluses and high glucose delivery rates in the first 24-48 h.
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