Evidence map›Paper›PMID 33279876›Full record

ArticleJournal of psychosomatic research2021

Association of perceived stress with health status outcomes in patients with peripheral artery disease.

Ali O Malik, Poghni Peri-Okonny, Kensey Gosch, Merrill B Thomas, Carlos Mena-Hurtado, William Hiatt, Herbert D Aronow, Phillip G Jones, Jeremy Provance, Clementine Labrosciano and 3 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Journal of psychosomatic research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01419080 (Patient-centered Outcomes Related to TReatment Practices in Peripheral Arterial Disease), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01419080 completednot on this map

Patient-centered Outcomes Related to TReatment Practices in Peripheral Arterial Disease: Investigating Trajectories (PORTRAIT Registry)

TypeobservationalSponsorSaint Luke's Health SystemRan2013 to 2016Enrolled797ConditionsPeripheral Arterial Disease, Quality of Life, Quality of Care
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Ali O MalikUniversity of Missouri Kansas City, Kansas City, MO, United States of America,; Saint Lukes' Mid America Heart Institute, Kansas City, MO, United States of America.
Poghni Peri-OkonnyUniversity of Missouri Kansas City, Kansas City, MO, United States of America,; Saint Lukes' Mid America Heart Institute, Kansas City, MO, United States of America.
Kensey GoschSaint Lukes' Mid America Heart Institute, Kansas City, MO, United States of America.
Merrill B ThomasUniversity of Missouri Kansas City, Kansas City, MO, United States of America.
Carlos Mena-HurtadoYale School of Medicine, Department of Internal Medicine, Vascular Medicine Outcomes Program, Yale University, New Haven, CT, United States of America.
William HiattUniversity of Colorado, Aurora, CO, United States of America.
Herbert D AronowAlpert Medical School of Brown University, Providence RI, Providence, United States of America.
Phillip G JonesUniversity of Missouri Kansas City, Kansas City, MO, United States of America,; Saint Lukes' Mid America Heart Institute, Kansas City, MO, United States of America.
Jeremy ProvanceUniversity of Missouri Kansas City, Kansas City, MO, United States of America.
Clementine LabroscianoUniversity of Adelaide, Adelaide, Australia.
Qurat-Ul-Ain JelaniYale School of Medicine, Department of Internal Medicine, Vascular Medicine Outcomes Program, Yale University, New Haven, CT, United States of America.
John A SpertusUniversity of Missouri Kansas City, Kansas City, MO, United States of America,; Saint Lukes' Mid America Heart Institute, Kansas City, MO, United States of America.
Kim G SmolderenYale School of Medicine, Department of Internal Medicine, Vascular Medicine Outcomes Program, Yale University, New Haven, CT, United States of America. Electronic address: kim.smolderen@yale.edu.
University of Missouri–Kansas City · USYale University · USSaint Luke's Hospital · USBrown University · USUniversity of Adelaide · AUUniversity of Colorado Anschutz Medical Campus · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
CARDIOVASCULAR OUTCOMES RESEARCH TRAINING PROGRAMT32HL110837 · NHLBI · UNIVERSITY OF MISSOURI KANSAS CITY · PI JOHN A SPERTUS · 2012 to 2026
$5.0M
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS T32 HL110837
6 · The paper itself

Abstract

objectiveTo assess association of chronic self-perceived stress with health status outcomes of patients with peripheral artery disease.

methodsThe PORTRAIT study is a prospective registry that enrolled 1275 patients with symptoms of peripheral artery disease across 16-sites in US, Netherlands, and Australia from June 2011 to December 2015. Demographics, comorbidities and diagnostic information was abstracted from chart review. Self-perceived stress was assessed using the 4-item perceived stress scale at baseline, 3- and 6-month follow-up. Scores range from 0 to 16 with higher scores indicating greater stress. Sum scores were calculated at each time point and averaged to quantify average exposure to stress from enrollment through 6 months. Disease-specific health status were assessed at baseline and 12-months using the peripheral artery disease questionnaire summary score.

resultsThe mean age of the analytical cohort (n = 1060) was 67.7 ± 9.3 years, 37.1% were females, and 82.3% were white. Comorbidities were highly prevalent with 80.9% having hypertension, 32.6% having diabetes, and 36.4% being smokers. In models adjusted for demographics, comorbidities, disease severity and socioeconomic status, having a higher average stress score was associated with poorer recovery (from baseline) in peripheral artery disease questionnaire summary score at 12-months (-1.4 points per +1-point increase in averaged 4-point perceived stress score, 95% CI -2.1, -0.6 p < 0.001).

conclusionIn patients with peripheral artery disease, experiencing higher chronic stress throughout the 6-months following their diagnosis, was independently associated with poorer recovery in 12-month disease-specific health status outcomes. (ClinicalTrial.gov identifier: NCT01419080).

Indexed as

Health StatusAgedCohort StudiesFemaleHumansMalePeripheral Arterial DiseaseProspective StudiesRegistriesSeverity of Illness IndexStress, PsychologicalChronic stressHealth statusPeripheral artery disease

Identifiers

PMID33279876
PMCPMC8130536
OpenAlexW3107070137

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.