Evidence map›Paper›PMID 33279804›Full record

ReviewCurrent opinion in neurobiology2021

Shedding light on learning and memory: optical interrogation of the synaptic circuitry.

Ju Lu, Yi Zuo

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Synaptic modifications in learning and memory - A dendritic spine story.Seminars in cell & developmental biology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ju LuDepartment of Molecular, Cell and Developmental Biology, University of California Santa Cruz, 1156 High Street, Santa Cruz, CA 95064, USA.
Yi ZuoDepartment of Molecular, Cell and Developmental Biology, University of California Santa Cruz, 1156 High Street, Santa Cruz, CA 95064, USA. Electronic address: yizuo@ucsc.edu.
University of California, Santa Cruz · US

Funding

Impact of sleep-wake circuits on cortical synapse plasticity during motor learningR01NS104950 · NINDS · STANFORD UNIVERSITY · PI MOURRAIN, PHILIPPE · 2018 to 2022
$2.6M
Contribution of astrocytes to the Fragile X SyndromeR01MH109475 · NIMH · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI ZUO, YI · 2016 to 2020
$2.0M
NIMH NIH HHS R01 MH109475NINDS NIH HHS R01 NS104950
6 · The paper itself

Abstract

In the quest for the physical substrate of learning and memory, a consensus gradually emerges that memory traces are stored in specific neuronal populations and the synaptic circuits that connect them. In this review, we discuss recent progresses in understanding the reorganization of synaptic circuits and neuronal assemblies associated with learning and memory, with an emphasis on optical techniques for in vivo interrogations. We also highlight some open questions on the missing link between synaptic modifications and neuronal coding, and how stable memory persists despite synaptic and neuronal fluctuations.

Indexed as

Neuronal PlasticitySynapsesLearningMemoryNeurons

Identifiers

PMID33279804
PMCPMC8172648
OpenAlexW3109815795

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.