Evidence map›Paper›PMID 33279794›Full record

ReviewCurrent opinion in neurobiology2020

Measuring and modeling whole-brain neural dynamics in Caenorhabditis elegans.

Francesco Randi, Andrew M Leifer

Open access · hybridAbstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Functional Neurogenomics to Dissect Disease Mechanisms Across Models.Annual review of genomics and human genetics · 2025
    Review
  6. Journal of biosciences · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Semantic Representation of Neural Circuit Knowledge inbioRxiv : the preprint server for biology · 2023
    Article
  14. Automatic monitoring of whole-body neural activity in behavingbioRxiv : the preprint server for biology · 2023
    Article
  15. TWISP: A Transgenic Worm for Interrogating Signal Propagation inbioRxiv : the preprint server for biology · 2023
    Article
  16. The role ofNeural regeneration research · 2023
    Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Francesco RandiDepartment of Physics, Princeton University, Jadwin Hall, Princeton, NJ 08544, USA.
Andrew M LeiferDepartment of Physics, Princeton University, Jadwin Hall, Princeton, NJ 08544, USA; Princeton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA. Electronic address: leifer@princeton.edu.
Princeton University · US

Funding

Probing Brain-wide Functional Connectivity During BehaviorDP2NS116768 · NINDS · PRINCETON UNIVERSITY · PI LEIFER, ANDREW MICHAEL · 2019 to 2019
$2.4M
NINDS NIH HHS DP2 NS116768
6 · The paper itself

Abstract

The compact nervous system of the nematode Caenorhabditis elegans makes it a powerful playground to study how neural dynamics constrained by neuroanatomy generate neural function and behavior. The ability to record neural activity from the whole brain simultaneously in this worm has opened several research avenues and is providing insights into brain-wide neural coding of locomotion, sleep, and other behaviors. We review these findings and the development of new methods, including new microscopes, new genetic tools, and new modeling approaches. We conclude with a discussion of the role of theory in interpreting or driving new experiments in C. elegans and potential paths forward.

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsAnimalsBrainLocomotionSleepCaenorhabditis elegans Proteins

Identifiers

PMID33279794
PMCPMC7801769
OpenAlexW3107998745

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.