Evidence map›Paper›PMID 33279630›Full record

ReviewAnnals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft2021

Lesions in the lungs of fatal corona virus disease Covid-19.

Colya N Englisch, Thomas Tschernig, Fidelis Flockerzi, Carola Meier, Rainer M Bohle

Open access · greenAbstract readReview
In one paragraph

Review in Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.4field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. COVID-19 Coagulopathy.Life (Basel, Switzerland) · 2024
    Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. COVID-19 pandemic in Uttarakhand, India: Environmental recovery or degradation?Journal of environmental chemical engineering · 2021
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Colya N EnglischInstitute of Anatomy and Cell Biology, Saarland University, Campus Homburg, Kirrberger Str., 66421 Homburg/Saar, Germany.
Thomas TschernigInstitute of Anatomy and Cell Biology, Saarland University, Campus Homburg, Kirrberger Str., 66421 Homburg/Saar, Germany. Electronic address: Thomas.Tschernig@uks.eu.
Fidelis FlockerziInstitute of Pathology, Saarland University, Homburg/Saar, Germany.
Carola MeierInstitute of Anatomy and Cell Biology, Saarland University, Campus Homburg, Kirrberger Str., 66421 Homburg/Saar, Germany.
Rainer M BohleInstitute of Pathology, Saarland University, Homburg/Saar, Germany.
Saarland University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The corona virus outbreak in Wuhan, China, at the end of 2019 has rapidly evolved into a pandemic which is still virulent in many countries. An infection with SARS-CoV-2 can lead to corona virus disease (Covid-19). This paper presents an overview of the knowledge gained so far with regard to histopathological lung lesions in fatal courses of Covid-19. The main findings were diffuse alveolar damage and micro-angiopathies. These included the development of hyaline membranes, thrombi, endothelial inflammation, haemorrhages and angiogenesis. Overall, the vessel lesions seemed to be more lethal than the diffuse alveolar damage. There was obvious hyperreactivity and hyperinflammation of the cellular immune system. An expanded T-cell memory may explain the increased risk of a severe course in the elderly.

Indexed as

AutopsyCOVID-19HumansLungPulmonary AlveoliSARS-CoV-2AngiogenesisCovid-19Diffuse alveolar damageHyaline membranesLung lesionsPathologyPerivascular inflammationSARS-CoV-2Thrombi

Identifiers

PMID33279630
PMCPMC7713602
OpenAlexW3109668047

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.